Red cell indices in wild-type (WT, ulk1+/+) and knockout (KO, ulk1−/−) mice
| . | WT, n = 10 . | KO, n = 10 . |
|---|---|---|
| RBC, ×1012/L | 10.6 ± 1.3 | 9.8 ± 0.7 |
| HGB, g/L | 164 ± 19 | 166 ± 13 |
| HCT | 0.529 ± 0.60 | 0.532 ± 0.045 |
| MCV, fL | 49.9 ± 1.8 | 54.5 ± 1.8* |
| MCH, pg | 15.5 ± 0.6 | 17.1 ± 0.7* |
| MCHC, g/L | 310 ± 5 | 314 ± 10 |
| RDW, % | 12.1 ± 0.6 | 15.1 ± 1.3* |
| Retic, % | 0.037 ± 0.05 | 0.179 ± 0.043 |
| Retic, ×109 cells/L | 389.7 ± 48.8 | 1735.7 ± 401.6* |
| MCV mature, fL | 51.1 ± 1.8 | 53.8 ± 1.4* |
| CHCM mature, g/dL | 30.1 ± 0.6 | 31.6 ± 1.2* |
| CH mature, pg | 15.4 ± 0.6 | 16.9 ± 0.7* |
| RDW mature, % | 11.4 ± 0.6 | 14.2 ± 1.1* |
| MCV retic, fL | 62.3 ± 1.9 | 65.1 ± 1.3* |
| CHCM retic, g/dL | 27.5 ± 0.5 | 28.8 ± 1.1* |
| CH retic, pg | 17.0 ± 0.7 | 18.7 ± 0.7* |
| RDW retic, % | 16.6 ± 0.9 | 12.7 ± 1.1* |
| . | WT, n = 10 . | KO, n = 10 . |
|---|---|---|
| RBC, ×1012/L | 10.6 ± 1.3 | 9.8 ± 0.7 |
| HGB, g/L | 164 ± 19 | 166 ± 13 |
| HCT | 0.529 ± 0.60 | 0.532 ± 0.045 |
| MCV, fL | 49.9 ± 1.8 | 54.5 ± 1.8* |
| MCH, pg | 15.5 ± 0.6 | 17.1 ± 0.7* |
| MCHC, g/L | 310 ± 5 | 314 ± 10 |
| RDW, % | 12.1 ± 0.6 | 15.1 ± 1.3* |
| Retic, % | 0.037 ± 0.05 | 0.179 ± 0.043 |
| Retic, ×109 cells/L | 389.7 ± 48.8 | 1735.7 ± 401.6* |
| MCV mature, fL | 51.1 ± 1.8 | 53.8 ± 1.4* |
| CHCM mature, g/dL | 30.1 ± 0.6 | 31.6 ± 1.2* |
| CH mature, pg | 15.4 ± 0.6 | 16.9 ± 0.7* |
| RDW mature, % | 11.4 ± 0.6 | 14.2 ± 1.1* |
| MCV retic, fL | 62.3 ± 1.9 | 65.1 ± 1.3* |
| CHCM retic, g/dL | 27.5 ± 0.5 | 28.8 ± 1.1* |
| CH retic, pg | 17.0 ± 0.7 | 18.7 ± 0.7* |
| RDW retic, % | 16.6 ± 0.9 | 12.7 ± 1.1* |
CH indicates corpuscular hemoglobin; CHCM, CH concentration mean; HGB, hemoglobin; HCT, hematocrit; MCH, mean corpuscular hemoglobin; MCHC, MCH concentration (calculated); MCV, mean corpuscular volume; RBC, red blood cells; RDW, red cell distribution width; and Retic, reticulocyte.
P < .005.