Distribution of scl genotypes in timed matings
| Genotypes . | sclWt/RER . | sclRER/RER . | |
|---|---|---|---|
| Alive . | Dead . | ||
| E8.5, % (n = 20) | 40 | 60 | |
| E9.5, % (n = 20) | 60 | 40 | |
| E12.5, % (n = 61) | 48 | 52 | |
| E14.5, % (n = 47) | 52 | 36 | 12 |
| E17.5, % (n = 10) | 50 | 20 | 30 |
| Expected, % | 50 | 50 | |
| Genotypes . | sclWt/RER . | sclRER/RER . | |
|---|---|---|---|
| Alive . | Dead . | ||
| E8.5, % (n = 20) | 40 | 60 | |
| E9.5, % (n = 20) | 60 | 40 | |
| E12.5, % (n = 61) | 48 | 52 | |
| E14.5, % (n = 47) | 52 | 36 | 12 |
| E17.5, % (n = 10) | 50 | 20 | 30 |
| Expected, % | 50 | 50 | |
Female sclWt/RER mice were crossed with male sclRER/RER mice. E8.5-E17.5 indicates embryonic days 8.5 to 17.5. The number of embryos analyzed are shown in the square brackets. Genotyping was performed by PCR (see Figure 1D). The first dead homozygous sclRER/RER embryos were observed at day E14.5.
Expected indicates the expected mendelian frequency.