Efficiency of engraftment following IUHCT with CD26-inhibited and noninhibited allogeneic BM
. | 5 mM Diprotin A: CD26 inhibition . | 0 mM Diprotin A: no inhibition . |
|---|---|---|
| Chimerism at any level, no. of chimeric mice/no. of mice analyzed (%) | 11/22 (50) | 9/40 (22.5) |
| Macrochimerism, no. of macrochimeric mice/no. of chimeric mice (%) | 11/11 (100) | 7/9 (77.7) |
. | 5 mM Diprotin A: CD26 inhibition . | 0 mM Diprotin A: no inhibition . |
|---|---|---|
| Chimerism at any level, no. of chimeric mice/no. of mice analyzed (%) | 11/22 (50) | 9/40 (22.5) |
| Macrochimerism, no. of macrochimeric mice/no. of chimeric mice (%) | 11/11 (100) | 7/9 (77.7) |
The number of BALB/c mice that were chimeric at 1 month of age after receiving either CD26-inhibited or noninhibited B6 GFP BM in utero was assessed.
*More than 1% donor chimerism.