Table 2. Gene expression analysis of GFP... | American Society of Hematology

Table 2.

Gene expression analysis of GFP⁺ LSK cells

Gene	MIG, AU	Smad7, AU	Fold difference Smad7 vs MIG
p18	0.33 ± 0.015	0.41 ± 0.054	1.22
p21*	0.47 ± 0.008	0.25 ± 0.005	- 1.88
p27	0.46 ± 0.025	0.41 ± 0.007	- 1.13
p57	ND	ND	ND
id2	0.009 ± 0.001	0.01 ± 0.0009	1.11
c-myc	7.25 ± 0.181	8.86 ± 1.21	1.22
gata2	1.18 ± 0.142	1.43 ± 0.061	1.21
hoxB4	ND	ND	ND
bmi1	0.15 ± 0.004	0.18 ± 0.003	1.21†
gfi1	0.03 ± 0.006	0.05 ± 0.009	1.42
hes1	ND	ND	ND
notch1	0.19 ± 0.03	0.24 ± 0.016	1.24
C/EBPa	0.29 ± 0.011	0.38 ± 0.007	1.31
c-mpl*	1.41 ± 0.237	2.18 ± 0.464	1.56
Ink*	0.012 ± 0.005	0.007 ± 0.0006	- 1.65
flt3	0.47 ± 0.046	0.62 ± 0.040	1.32
spry2	0.16 ± 0.014	0.19 ± 0.022	1.18
smad7‡	.055‡	6.85‡	124

Gene	MIG, AU	Smad7, AU	Fold difference Smad7 vs MIG
p18	0.33 ± 0.015	0.41 ± 0.054	1.22
p21*	0.47 ± 0.008	0.25 ± 0.005	- 1.88
p27	0.46 ± 0.025	0.41 ± 0.007	- 1.13
p57	ND	ND	ND
id2	0.009 ± 0.001	0.01 ± 0.0009	1.11
c-myc	7.25 ± 0.181	8.86 ± 1.21	1.22
gata2	1.18 ± 0.142	1.43 ± 0.061	1.21
hoxB4	ND	ND	ND
bmi1	0.15 ± 0.004	0.18 ± 0.003	1.21†
gfi1	0.03 ± 0.006	0.05 ± 0.009	1.42
hes1	ND	ND	ND
notch1	0.19 ± 0.03	0.24 ± 0.016	1.24
C/EBPa	0.29 ± 0.011	0.38 ± 0.007	1.31
c-mpl*	1.41 ± 0.237	2.18 ± 0.464	1.56
Ink*	0.012 ± 0.005	0.007 ± 0.0006	- 1.65
flt3	0.47 ± 0.046	0.62 ± 0.040	1.32
spry2	0.16 ± 0.014	0.19 ± 0.022	1.18
smad7‡	.055‡	6.85‡	124

AUs indicate arbitrary units; and ND, not detectable.

Fold difference > 1.5.

P = .003.

Representative experiment.