Correlation of TAA expression and specific immune responses (CTLs) against the respective TAA
. | CTL, no. patients . | . | . | ||
---|---|---|---|---|---|
TAA expression* . | Yes . | No . | Total . | ||
High | 12 | 3 | 15 | ||
Low | 3 | 7 | 10 | ||
Total | 15 | 10 | 25 |
. | CTL, no. patients . | . | . | ||
---|---|---|---|---|---|
TAA expression* . | Yes . | No . | Total . | ||
High | 12 | 3 | 15 | ||
Low | 3 | 7 | 10 | ||
Total | 15 | 10 | 25 |
The difference between proportions was 0.500; the 95% CI was 0.151-0.849 (normal approximation); and the 2-tailed P was .036 (exact, double 1-tailed P).
TAA expression was considered as high (1) by an expression value greater than or equal to the median expression level of the respective TAA across all samples for real-time RT-PCR and/or microarray analysis and (2) by a positive conventional RT-PCR result.