Table 1. TAA expression in patients with... | American Society of Hematology

Table 1.

TAA expression in patients with AML (n = 116): correlation with clinical parameters

	*BCL2*	*CA9*	*HMMR*	*LAMR1*	*PRAME*	*PRTN3*	*TERT*	*WT1*	No vs at least 1 TAA
Older than 60 y, P	NS	NS	NS	NS	NS	NS	NS	NS	<.001
WBC count below 30 × 10⁹/L, P	NS	NS	.027	.002	NS	NS	NS	NS	NS
LDH above median, P	NS	NS	NS	NS	NS	NS	NS	NS	NS
Secondary AML, P	NS	NS	NS	.047	.020	NS	NS	NS	NS
Karyotype subgroups, P	NS	.004	NS	.044	.001	.001	NS	NS	NS
t(15;17)	NS	↓	NS	=	↑	↑	NS	NS	NS
t(8;21)	NS	=	NS	↑	↑	↑	NS	NS	NS
inv(16)	NS	=	NS	=	↓	↑	NS	NS	NS
t(9;11)	NS	↑	NS	=	=	↓	NS	NS	NS
Normal karyotype	NS	=	NS	↓	↓	↓	NS	NS	NS
+8 sole	NS	=	NS	↓	=	↑	NS	NS	NS
-7/del(7q)	NS	↑	NS	↑	↑	↓	NS	NS	NS
Complex karyotype	NS	↓	NS	=	↓	↓	NS	NS	NS
Others	NS	=	NS	↑	↓	↓	NS	NS	NS
FLT3 ITD, P	NS	NS	NS	NS	NS	NS	NS	.046	NS
MLL PTD, P	NS	NS	NS	NS	NS	NS	NS	NS	NS

	*BCL2*	*CA9*	*HMMR*	*LAMR1*	*PRAME*	*PRTN3*	*TERT*	*WT1*	No vs at least 1 TAA
Older than 60 y, P	NS	NS	NS	NS	NS	NS	NS	NS	<.001
WBC count below 30 × 10⁹/L, P	NS	NS	.027	.002	NS	NS	NS	NS	NS
LDH above median, P	NS	NS	NS	NS	NS	NS	NS	NS	NS
Secondary AML, P	NS	NS	NS	.047	.020	NS	NS	NS	NS
Karyotype subgroups, P	NS	.004	NS	.044	.001	.001	NS	NS	NS
t(15;17)	NS	↓	NS	=	↑	↑	NS	NS	NS
t(8;21)	NS	=	NS	↑	↑	↑	NS	NS	NS
inv(16)	NS	=	NS	=	↓	↑	NS	NS	NS
t(9;11)	NS	↑	NS	=	=	↓	NS	NS	NS
Normal karyotype	NS	=	NS	↓	↓	↓	NS	NS	NS
+8 sole	NS	=	NS	↓	=	↑	NS	NS	NS
-7/del(7q)	NS	↑	NS	↑	↑	↓	NS	NS	NS
Complex karyotype	NS	↓	NS	=	↓	↓	NS	NS	NS
Others	NS	=	NS	↑	↓	↓	NS	NS	NS
FLT3 ITD, P	NS	NS	NS	NS	NS	NS	NS	.046	NS
MLL PTD, P	NS	NS	NS	NS	NS	NS	NS	NS	NS

NS indicates not significant (P > .05); higher expression levels compared to the mean expression of the respective TAA; =, mean expression of the respective TAA; ↓, lower expression levels compared to the mean expression of the respective TAA; and PTD, partial tandem duplication.

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