Patient characteristics
. | Patients with FL . | . | Patients with MCL . | . | ||
---|---|---|---|---|---|---|
Characteristic . | Observation . | R-maintenance . | Observation . | R-maintenance . | ||
No. of patients | 53 | 52 | 29 | 28 | ||
Median age, y (range) | 61 (35-80) | 59 (41-78) | 63 (39-78) | 63 (49-74) | ||
Age at least 60 y, no. (%) | 29 (55) | 25 (48) | 22 (76) | 22 (79) | ||
Sex, no. (%) | ||||||
Male | 27 (51) | 22 (42) | 23 (79) | 18 (64) | ||
Female | 26 (49) | 30 (58) | 6 (21) | 10 (36) | ||
No. of prior therapies, % | ||||||
1 | 73 | 67 | 79 | 86 | ||
2 | 17 | 27 | 21 | 11 | ||
More than 2 | 9 | 6 | 0 | 4 | ||
Previous PBCT, % | 4 | 8 | 3 | 11 | ||
Response to prior treatment, % | 89 | 94 | 90 | 89 | ||
Extranodal involvement, % | ||||||
Bone marrow | 52 | 43 | 61 | 70 | ||
Liver | 6 | 0 | 0 | 8 | ||
GI tract | 4 | 2 | 30 | 25 | ||
Spleen | 27 | 20 | 39 | 33 | ||
B symptoms | 28 | 21 | 24 | 18 | ||
Elevated LDH, % | 20 | 20 | 11 | 21 | ||
Initial therapy, no. (%) | ||||||
FCM | 13 (25) | 11 (21) | 4 (14) | 6 (21) | ||
R-FCM | 40 (75) | 41 (79) | 25 (86) | 22 (79) |
. | Patients with FL . | . | Patients with MCL . | . | ||
---|---|---|---|---|---|---|
Characteristic . | Observation . | R-maintenance . | Observation . | R-maintenance . | ||
No. of patients | 53 | 52 | 29 | 28 | ||
Median age, y (range) | 61 (35-80) | 59 (41-78) | 63 (39-78) | 63 (49-74) | ||
Age at least 60 y, no. (%) | 29 (55) | 25 (48) | 22 (76) | 22 (79) | ||
Sex, no. (%) | ||||||
Male | 27 (51) | 22 (42) | 23 (79) | 18 (64) | ||
Female | 26 (49) | 30 (58) | 6 (21) | 10 (36) | ||
No. of prior therapies, % | ||||||
1 | 73 | 67 | 79 | 86 | ||
2 | 17 | 27 | 21 | 11 | ||
More than 2 | 9 | 6 | 0 | 4 | ||
Previous PBCT, % | 4 | 8 | 3 | 11 | ||
Response to prior treatment, % | 89 | 94 | 90 | 89 | ||
Extranodal involvement, % | ||||||
Bone marrow | 52 | 43 | 61 | 70 | ||
Liver | 6 | 0 | 0 | 8 | ||
GI tract | 4 | 2 | 30 | 25 | ||
Spleen | 27 | 20 | 39 | 33 | ||
B symptoms | 28 | 21 | 24 | 18 | ||
Elevated LDH, % | 20 | 20 | 11 | 21 | ||
Initial therapy, no. (%) | ||||||
FCM | 13 (25) | 11 (21) | 4 (14) | 6 (21) | ||
R-FCM | 40 (75) | 41 (79) | 25 (86) | 22 (79) |
PBCT indicates peripheral blood cell transplantation; GI, gastrointestinal.