Table 2.

Lymphoid-cell numbers in MRL/lpr and C57BL/6J mice treated by As2O3


Blood
Treatment*
Thymus
Bone marrow
Red cells
White cells
Spleen
Mesenteric LN
MRL/lpr       
    PBS   5.4 ± 1.54   3.2 ± 0.2   6.55 ± 1   14.92 ± 4.4   37 ± 8.6   55 ± 15  
    As2O3  5.45 ± 0.83   3.23 ± 0.69   6.16 ± 0.40   6.15 ± 0.55   11 ± 3.12   14 ± 3.44  
C57BL/6J       
    PBS   6.28 ± 0.59   4.1 ± 0.45   5.98 ± 0.81   9.1 ± 0.46   7 ± 0.58   1.57 ± 0.28  
    As2O3
 
5.16 ± 0.55
 
4.76 ± 0.41
 
5.5 ± 0.59
 
7.28 ± 0.78
 
7.15 ± 0.75
 
1.77 ± 0.27
 

Blood
Treatment*
Thymus
Bone marrow
Red cells
White cells
Spleen
Mesenteric LN
MRL/lpr       
    PBS   5.4 ± 1.54   3.2 ± 0.2   6.55 ± 1   14.92 ± 4.4   37 ± 8.6   55 ± 15  
    As2O3  5.45 ± 0.83   3.23 ± 0.69   6.16 ± 0.40   6.15 ± 0.55   11 ± 3.12   14 ± 3.44  
C57BL/6J       
    PBS   6.28 ± 0.59   4.1 ± 0.45   5.98 ± 0.81   9.1 ± 0.46   7 ± 0.58   1.57 ± 0.28  
    As2O3
 
5.16 ± 0.55
 
4.76 ± 0.41
 
5.5 ± 0.59
 
7.28 ± 0.78
 
7.15 ± 0.75
 
1.77 ± 0.27
 
*

Two-month-old mice were treated for 2 months with As2O3 (5 μg/g) or PBS daily, n = 9 (mice per group).

Cell number × 107 ± SE.

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