Table 3. Characteristics of Mutations of... | American Society of Hematology

Table 3.

Characteristics of Mutations of BCL-6 5′ Noncoding Regions in CHD Cell Lines

Cell Line	Nucleotide Substitution^*	Mutation Status	Mutation Frequency^† (×10⁻³/bp)
L-428	G → A (438), T → A (448), C → T (475), T → G (557), T → C (602), T → C (646), A → G (657), A → C (693), T → C (840), C → G (904), T → C (1042), A → C (1063), A → G (1064), A → C (1071)	Heterozygous	9.47
SUP-HD1	G → T (440), G → A (478), G → A (488), C → G (520), C → A (522), C → A (525), C → A (526), T → G (557), A → G (643), G → A (648), G → A (758), C → G (771), C → G (779), T → A (782), C → G (788), T → C (792), ΔT (836), C → T (875), T → G (908), T → G (911), T → G (924), T → C (927), G → A (952), C → G (959), G → A (966), T → A (980), G → A (981), G → A (1002), A → T (1051), T → G (1104)	Homo-/hemizygous^‡	29.8
KM-H2	G → A (962)	Homo-/hemizygous^‡	1.35

Cell Line	Nucleotide Substitution^*	Mutation Status	Mutation Frequency^† (×10⁻³/bp)
L-428	G → A (438), T → A (448), C → T (475), T → G (557), T → C (602), T → C (646), A → G (657), A → C (693), T → C (840), C → G (904), T → C (1042), A → C (1063), A → G (1064), A → C (1071)	Heterozygous	9.47
SUP-HD1	G → T (440), G → A (478), G → A (488), C → G (520), C → A (522), C → A (525), C → A (526), T → G (557), A → G (643), G → A (648), G → A (758), C → G (771), C → G (779), T → A (782), C → G (788), T → C (792), ΔT (836), C → T (875), T → G (908), T → G (911), T → G (924), T → C (927), G → A (952), C → G (959), G → A (966), T → A (980), G → A (981), G → A (1002), A → T (1051), T → G (1104)	Homo-/hemizygous^‡	29.8
KM-H2	G → A (962)	Homo-/hemizygous^‡	1.35

*The nucleotide position is indicated in brackets. Δ, deletion.

Frequency of mutated/tested nucleotides.

The wild-type sequence of BCL-6 was not detectable in this case.