Search for Minimal Residual Disease in Specimens That Were Normal by Q-Cytogenetics for 25 Metaphases and D-FISH for 500 Nuclei
| Pt . | Spec . | 500 Nuclei . | 6,000 Nuclei . | Hypermetaphase Bone Marrow % Abn (Ph Positive/Metaphases Analyzed) . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Bone Marrow . | Peripheral Blood . | Bone Marrow . | Peripheral Blood . | |||||||
| % Abn . | Abn Nuclei . | % Abn . | Abn Nuclei . | % Abn . | Abn Nuclei . | % Abn . | Abn Nuclei . | |||
| 4 | 3 | 0.6 | 3 | 0.2 | 1 | 0.22 | 13 | 0.10 | 6 | 0.0 (0/27) |
| 4 | 4 | 0.4 | 2 | 0.2 | 1 | 0.23 | 14 | 0.08 | 5 | 0.0 (0/15) |
| 4 | 5 | 0.0 | 0 | 0.0 | 0 | NA | NA | 0.13 | 8 | 0.6 (1/169) |
| 5 | 3 | 0.6 | 3 | 1.0 | 5 | 1.30 | 78 | 0.95 | 57 | 0.0 (0/136) |
| 5 | 4 | 0.0 | 0 | 0.2 | 1 | 0.05 | 3 | 0.12 | 7 | 0.0 (0/126) |
| Normal cut-off | >0.8 | >4 | >0.8 | >4 | >0.079 | >4 | >0.079 | >4 | ||
| Pt . | Spec . | 500 Nuclei . | 6,000 Nuclei . | Hypermetaphase Bone Marrow % Abn (Ph Positive/Metaphases Analyzed) . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Bone Marrow . | Peripheral Blood . | Bone Marrow . | Peripheral Blood . | |||||||
| % Abn . | Abn Nuclei . | % Abn . | Abn Nuclei . | % Abn . | Abn Nuclei . | % Abn . | Abn Nuclei . | |||
| 4 | 3 | 0.6 | 3 | 0.2 | 1 | 0.22 | 13 | 0.10 | 6 | 0.0 (0/27) |
| 4 | 4 | 0.4 | 2 | 0.2 | 1 | 0.23 | 14 | 0.08 | 5 | 0.0 (0/15) |
| 4 | 5 | 0.0 | 0 | 0.0 | 0 | NA | NA | 0.13 | 8 | 0.6 (1/169) |
| 5 | 3 | 0.6 | 3 | 1.0 | 5 | 1.30 | 78 | 0.95 | 57 | 0.0 (0/136) |
| 5 | 4 | 0.0 | 0 | 0.2 | 1 | 0.05 | 3 | 0.12 | 7 | 0.0 (0/126) |
| Normal cut-off | >0.8 | >4 | >0.8 | >4 | >0.079 | >4 | >0.079 | >4 | ||
Abbreviations: Abn, abnormal; NA, not available; spec, specimen.