Association Between the Presence of the NdeI Site and α2 Genotype
| Genotype α2 Alleles . | Nde I Site . | Br Type . | ||||
|---|---|---|---|---|---|---|
| Complete Digest . | Partial Digest . | Undigested . | a/a . | a/b . | b/b . | |
| 1/1 | 4 | 0 | 0 | 0 | 0 | 12 |
| 2/2 | 5 | 0 | 0 | 0 | 0 | 17 |
| 1/2 | 7 | 0 | 0 | 0 | 0 | 21 |
| 1/3 | 0 | 2 | 0 | 0 | 4 | 0 |
| 2/3 | 0 | 5 | 0 | 0 | 9 | 0 |
| 3/3 | — | — | — | — | — | — |
| Genotype α2 Alleles . | Nde I Site . | Br Type . | ||||
|---|---|---|---|---|---|---|
| Complete Digest . | Partial Digest . | Undigested . | a/a . | a/b . | b/b . | |
| 1/1 | 4 | 0 | 0 | 0 | 0 | 12 |
| 2/2 | 5 | 0 | 0 | 0 | 0 | 17 |
| 1/2 | 7 | 0 | 0 | 0 | 0 | 21 |
| 1/3 | 0 | 2 | 0 | 0 | 4 | 0 |
| 2/3 | 0 | 5 | 0 | 0 | 9 | 0 |
| 3/3 | — | — | — | — | — | — |
Allelic genotype combinations are depicted in the first column. Individuals homozygous for allele 3 have not yet been detected in this study. The patterns of Nde I digestion were determined, as per the examples depicted in Fig 2B. Br typing was performed as described in Materials and Methods. The number of individuals whose DNA amplicon gave the representative digestion pattern with NdeI is depicted for each allelic genotype.