Response Rate According to Randomization
| . | Randomization Group . | P Value . | |||
|---|---|---|---|---|---|
| 6Mpred 2 mg/kg . | 6Mpred 10 mg/kg . | ||||
| No . | Yes . | No . | Yes . | ||
| No. of patients responding* | 14 | 32 | 13 | 34 | .9 |
| Age | |||||
| ≤20 yr | 6 | 12 | 4 | 11 | |
| >20 yr | 8 | 20 | 9 | 23 | .9 |
| GvHD Prophylaxis | |||||
| CS | 11 | 14 | 7 | 16 | |
| CS + MTX | 3 | 18 | 6 | 18 | .3 |
| Conditioning | |||||
| No TBI | 8 | 25 | 8 | 25 | |
| TBI | 6 | 7 | 5 | 9 | .5 |
| Disease status | |||||
| 1ST CR | 6 | 19 | 5 | 18 | |
| >1ST CR | 8 | 13 | 8 | 16 | .8 |
| Interval (d) BMT-TX | |||||
| ≤12 | 8 | 19 | 7 | 17 | |
| >12 | 6 | 13 | 6 | 17 | .7 |
| . | Randomization Group . | P Value . | |||
|---|---|---|---|---|---|
| 6Mpred 2 mg/kg . | 6Mpred 10 mg/kg . | ||||
| No . | Yes . | No . | Yes . | ||
| No. of patients responding* | 14 | 32 | 13 | 34 | .9 |
| Age | |||||
| ≤20 yr | 6 | 12 | 4 | 11 | |
| >20 yr | 8 | 20 | 9 | 23 | .9 |
| GvHD Prophylaxis | |||||
| CS | 11 | 14 | 7 | 16 | |
| CS + MTX | 3 | 18 | 6 | 18 | .3 |
| Conditioning | |||||
| No TBI | 8 | 25 | 8 | 25 | |
| TBI | 6 | 7 | 5 | 9 | .5 |
| Disease status | |||||
| 1ST CR | 6 | 19 | 5 | 18 | |
| >1ST CR | 8 | 13 | 8 | 16 | .8 |
| Interval (d) BMT-TX | |||||
| ≤12 | 8 | 19 | 7 | 17 | |
| >12 | 6 | 13 | 6 | 17 | .7 |
*Two patients were considered not evaluable for response.
Abbreviation: 1st CR, first complete remission.