Table 1. BCR-ABL and ABL-BCR expression... | American Society of Hematology

Table 1.

BCR-ABL and ABL-BCR expression in CML patients

Fusion gene	Transcript expressed	No. (%) of patients
BCR-ABL	b2a2	216 (42)
	b3a2	250 (48)
	b2a2 & b3a2	48 (9)
	Other^*	5 (2)
	Total	519 (100)
ABL(1b)-BCR	Positive	282 (54)
	1bb3	41
	1bb4	196
	1bb3 & 1bb4	38
	Other^†	7
	Negative	237 (46)
ABL(1a)-BCR	Positive	44 (8)
	1ab3	3
	1ab4	30
	1ab3 & 1ab4	9
	Other^‡	2
	Negative	475 (92)

Fusion gene	Transcript expressed	No. (%) of patients
BCR-ABL	b2a2	216 (42)
	b3a2	250 (48)
	b2a2 & b3a2	48 (9)
	Other^*	5 (2)
	Total	519 (100)
ABL(1b)-BCR	Positive	282 (54)
	1bb3	41
	1bb4	196
	1bb3 & 1bb4	38
	Other^†	7
	Negative	237 (46)
ABL(1a)-BCR	Positive	44 (8)
	1ab3	3
	1ab4	30
	1ab3 & 1ab4	9
	Other^‡	2
	Negative	475 (92)

b2a3 = 3, e1a2 = 1, e19a2 = 1.

1bb6 = 2, 1bb2 = 1, with variable intervening sequence between ABL and BCR exons = 4, as described.15

1aa6 = 2.