Clinical and laboratory findings of 21 patients with mixed cryoglobulinemia
| Patient no. . | Age (y)/sex . | ALT (IU/L) . | Histology . | Disease duration (mo) . | Cryocrit % . | Monoclonal component . | RF (IU/L) . | Lymphoma . | HCV-HVR1 mutated . |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 67/F | 29 | Cirrhosis | 204 | 3 | IgM/k | 429 | NA | + |
| 2 | 61/F | 76 | Mild | 96 | 3 | IgM/k | 165 | NA | + |
| 3 | 71/F | 24 | Severe | 120 | 10 | IgM/k | 57 | NHL | + |
| 4 | 60/M | 14 | Mild | 12 | 3 | IgM/k | 38 | NA | + |
| 5 | 66/F | 162 | Cirrhosis | 68 | 1 | IgM/k | 89 | NO | + |
| 6 | 64/M | 24 | Mild | 108 | 5 | IgM/k | < 30 | NO | + |
| 7 | 73/F | 28 | Mild | 114 | 5 | IgM/k | 109 | NO | − |
| 8 | 67/F | 78 | Cirrhosis | 132 | 2 | IgM/k | < 30 | NA | − |
| 9 | 69/F | 25 | Mild | 66 | 5 | IgM/k | 437 | NA | − |
| 10 | 75/M | 31 | Mild | 60 | 5 | IgM/k | 325 | NA | − |
| 11 | 50/F | 49 | Mild | 156 | 9 | IgM/k | 82 | NHL | − |
| 12 | 59/F | 14 | Mild | 110 | 2 | IgM/k | 55 | NHL | − |
| 13 | 53/M | 33 | Moderate | 54 | 5 | IgM/k | 245 | NA | − |
| 14 | 67/F | 68 | Moderate | 50 | 0.5 | IgM/k | < 30 | NO | − |
| 15 | 53/F | 15 | Mild | 93 | 1 | IgM/λ | < 30 | NA | − |
| 16 | 55/F | 97 | Severe | 72 | 3 | IgM/k | 159 | NO | − |
| 17 | 45/M | 32 | NA | 204 | 3 | IgM/k | 545 | NO | − |
| 18 | 77/F | 104 | NA | 84 | 0.5 | IgM/k | 58 | NA | − |
| 19 | 69/F | 113 | Severe | 90 | 1 | IgM/k | 250 | NO | − |
| 20 | 68/F | 60 | Mild | 48 | 0.5 | IgM/λ | 1450 | NA | − |
| 21 | 44/F | 43 | Cirrhosis | 75 | 1 | IgM/k | 122 | NO | − |
| Patient no. . | Age (y)/sex . | ALT (IU/L) . | Histology . | Disease duration (mo) . | Cryocrit % . | Monoclonal component . | RF (IU/L) . | Lymphoma . | HCV-HVR1 mutated . |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 67/F | 29 | Cirrhosis | 204 | 3 | IgM/k | 429 | NA | + |
| 2 | 61/F | 76 | Mild | 96 | 3 | IgM/k | 165 | NA | + |
| 3 | 71/F | 24 | Severe | 120 | 10 | IgM/k | 57 | NHL | + |
| 4 | 60/M | 14 | Mild | 12 | 3 | IgM/k | 38 | NA | + |
| 5 | 66/F | 162 | Cirrhosis | 68 | 1 | IgM/k | 89 | NO | + |
| 6 | 64/M | 24 | Mild | 108 | 5 | IgM/k | < 30 | NO | + |
| 7 | 73/F | 28 | Mild | 114 | 5 | IgM/k | 109 | NO | − |
| 8 | 67/F | 78 | Cirrhosis | 132 | 2 | IgM/k | < 30 | NA | − |
| 9 | 69/F | 25 | Mild | 66 | 5 | IgM/k | 437 | NA | − |
| 10 | 75/M | 31 | Mild | 60 | 5 | IgM/k | 325 | NA | − |
| 11 | 50/F | 49 | Mild | 156 | 9 | IgM/k | 82 | NHL | − |
| 12 | 59/F | 14 | Mild | 110 | 2 | IgM/k | 55 | NHL | − |
| 13 | 53/M | 33 | Moderate | 54 | 5 | IgM/k | 245 | NA | − |
| 14 | 67/F | 68 | Moderate | 50 | 0.5 | IgM/k | < 30 | NO | − |
| 15 | 53/F | 15 | Mild | 93 | 1 | IgM/λ | < 30 | NA | − |
| 16 | 55/F | 97 | Severe | 72 | 3 | IgM/k | 159 | NO | − |
| 17 | 45/M | 32 | NA | 204 | 3 | IgM/k | 545 | NO | − |
| 18 | 77/F | 104 | NA | 84 | 0.5 | IgM/k | 58 | NA | − |
| 19 | 69/F | 113 | Severe | 90 | 1 | IgM/k | 250 | NO | − |
| 20 | 68/F | 60 | Mild | 48 | 0.5 | IgM/λ | 1450 | NA | − |
| 21 | 44/F | 43 | Cirrhosis | 75 | 1 | IgM/k | 122 | NO | − |
ALT indicates serum alanine aminotransferase; NA, not available; NHL, non-Hodgkin lymphoma.