Table 1.

Bone marrow cell classification of erythroleukemia (M6) cases as well as cases with high level of expression ofTfR2-α messenger RNA

Sample no.DiagnosisExpression (% K562)BM (%)
TfR2-αTfR2-βTfR1BlastErythroid
28* M6 141 311 217 12 54 
198 M6 93 46 68 28 
M6-1* M6 101 103 161 35 43 
M6-3* M6 159 324 184 91 
M6-4* M6 152 279 170 48 
M6-5 M6 39 63 109 81 
M6-6 M6 84 158 26 16 
219* CML 75 278 73 15 
201* RARS 89 299 113 55 
230* RAEB 197 726 233 11 32 
236* RAEB 69 365 152 35 
55* RAEBT 61 148 103 43 
Nonmalignant
BM, mean ± SD 
 23 ± 17 188 ± 66 62 ± 17   
Sample no.DiagnosisExpression (% K562)BM (%)
TfR2-αTfR2-βTfR1BlastErythroid
28* M6 141 311 217 12 54 
198 M6 93 46 68 28 
M6-1* M6 101 103 161 35 43 
M6-3* M6 159 324 184 91 
M6-4* M6 152 279 170 48 
M6-5 M6 39 63 109 81 
M6-6 M6 84 158 26 16 
219* CML 75 278 73 15 
201* RARS 89 299 113 55 
230* RAEB 197 726 233 11 32 
236* RAEB 69 365 152 35 
55* RAEBT 61 148 103 43 
Nonmalignant
BM, mean ± SD 
 23 ± 17 188 ± 66 62 ± 17   

Expression of TfR1, TfR2-α, and TfR2-βmessenger RNA was analyzed by semiquantitative reverse-transcriptase polymerase chain reaction and shown as a percentage of the level detected in K562 cells. As reference, the mean ± SD of expression levels of nonmalignant marrow samples are shown in the bottom row (control).

*

Samples that had high levels of expression ofTfR2 mRNA (greater than 60% K562).

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