Table 1.

Engraftment rate in different groups of NOD-SCID mice injected with different cell populations

Cell populationPrimary CD34+cellsLZRS-EGFP–transduced cellsLZRS-Ik6-EGFP–transduced cells
Unsorted cellsSorted
EGFP+ cells
Sorted
EGFP cells
Unsorted cellsSorted
EGFP+ cells
Sorted
EGFP cells
No. of animals 27 28 12 34 12 14 
CD45+ cells > 0.1% 22 11 11  
CD45+cells > 1% 13 4* 3* 10 
Cell populationPrimary CD34+cellsLZRS-EGFP–transduced cellsLZRS-Ik6-EGFP–transduced cells
Unsorted cellsSorted
EGFP+ cells
Sorted
EGFP cells
Unsorted cellsSorted
EGFP+ cells
Sorted
EGFP cells
No. of animals 27 28 12 34 12 14 
CD45+ cells > 0.1% 22 11 11  
CD45+cells > 1% 13 4* 3* 10 

Hematopoietic reconstitution of animals from the control and test groups is described in Table 2 and Figure 5.

*

Animals in the control group.

Animals in the test group.

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