Recovery of Gr B and TPH mRNA Expression inmi/mi CMCs After Introduction of +-MITF cDNA
| Cells . | Proportion to Alcian Blue+ Cells (%)* . | |||
|---|---|---|---|---|
| Gr B mRNA+ Cells . | TPH mRNA+ Cells . | HDC mRNA+ Cells . | MC-CPA mRNA+ Cells . | |
| +/+ CMCs | 88 ± 4 | 70 ± 4 | 72 ± 2 | 91 ± 2 |
| mi/mi CMCs | 6 ± 3-151 | 13 ± 1-151 | 79 ± 6 | 93 ± 2 |
| mi/mi CMCs overexpressing +-MITF | 73 ± 8 | 68 ± 3 | 79 ± 2 | 93 ± 2 |
| mi/mi CMCs overexpressing mi-MITF | 7 ± 3-151 | 11 ± 3-151 | 82 ± 1 | 90 ± 2 |
| Cells . | Proportion to Alcian Blue+ Cells (%)* . | |||
|---|---|---|---|---|
| Gr B mRNA+ Cells . | TPH mRNA+ Cells . | HDC mRNA+ Cells . | MC-CPA mRNA+ Cells . | |
| +/+ CMCs | 88 ± 4 | 70 ± 4 | 72 ± 2 | 91 ± 2 |
| mi/mi CMCs | 6 ± 3-151 | 13 ± 1-151 | 79 ± 6 | 93 ± 2 |
| mi/mi CMCs overexpressing +-MITF | 73 ± 8 | 68 ± 3 | 79 ± 2 | 93 ± 2 |
| mi/mi CMCs overexpressing mi-MITF | 7 ± 3-151 | 11 ± 3-151 | 82 ± 1 | 90 ± 2 |
*Mean ± SE of three experiments.
P < .01 by t-test when compared with the value of +/+ CMCs.