Hematologic Profile of Mice With Combined Deficiency of Nrf-2 and NF-E2
| No. . | Genotype (Nrf2/NF-E2) . | Hct (%) . | Hb (g/dL) . | RBC (×106/μL) . | WBC (×103/μL) . | Platelets (×106/μL)-150 . |
|---|---|---|---|---|---|---|
| 15 | (+/+)/(+/+) | 46.9 ± 2.8-151 | 15.0 ± 0.8 | 7.7 ± 1.0 | 4.4 ± 1.2 | 1.25 |
| 8 | (−/−)/(+/+) | 46.1 ± 1.7 | 15.2 ± 0.7 | 7.6 ± 0.5 | 5.1 ± 2.3 | ND-152 |
| 5 | (−/−)/(+/−) | 46.2 ± 3.1 | 14.9 ± 1.1 | 8.0 ± 0.5 | 4.3 ± 2.4 | ND |
| 8 | (+/+)/(−/−) | 42.1 ± 4.5 | 13.0 ± 1.5 | 7.7 ± 1.0 | 4.4 ± 1.1 | 0.04 |
| 4 | (+/−)/(−/−) | 40.5 ± 3.3 | 11.9 ± 1.1 | 7.5 ± 0.8 | 4.6 ± 2.3 | ND |
| 4 | (−/−)/(−/−) | 41.8 ± 4.4 | 12.3 ± 1.5 | 7.9 ± 1.2 | 5.6 ± 1.4 | 0.03 |
| No. . | Genotype (Nrf2/NF-E2) . | Hct (%) . | Hb (g/dL) . | RBC (×106/μL) . | WBC (×103/μL) . | Platelets (×106/μL)-150 . |
|---|---|---|---|---|---|---|
| 15 | (+/+)/(+/+) | 46.9 ± 2.8-151 | 15.0 ± 0.8 | 7.7 ± 1.0 | 4.4 ± 1.2 | 1.25 |
| 8 | (−/−)/(+/+) | 46.1 ± 1.7 | 15.2 ± 0.7 | 7.6 ± 0.5 | 5.1 ± 2.3 | ND-152 |
| 5 | (−/−)/(+/−) | 46.2 ± 3.1 | 14.9 ± 1.1 | 8.0 ± 0.5 | 4.3 ± 2.4 | ND |
| 8 | (+/+)/(−/−) | 42.1 ± 4.5 | 13.0 ± 1.5 | 7.7 ± 1.0 | 4.4 ± 1.1 | 0.04 |
| 4 | (+/−)/(−/−) | 40.5 ± 3.3 | 11.9 ± 1.1 | 7.5 ± 0.8 | 4.6 ± 2.3 | ND |
| 4 | (−/−)/(−/−) | 41.8 ± 4.4 | 12.3 ± 1.5 | 7.9 ± 1.2 | 5.6 ± 1.4 | 0.03 |