Table 4. Univariate and Multivariate... | American Society of Hematology

Table 4.

Univariate and Multivariate Analysis of the Prognostic Value of the Different Clinico-Biological Characteristics in MM With Respect to OS

Variable	Percentage of Cases	Median OS (mo)	P Value Univariate Analysis	P Value Multivariate Analysis
S-phase PC
<3%	68	39	<.0001	.010
≥3%	32	15
β₂microglobulin
<6 mg/L	69	44	.0030	.024
≥6 mg/L	31	15
Chromosome 13
Monosomy	33	14	.0012	.031
Normal	67	60
Chromosome 6
Trisomy	27	70	.0330	.048
Nontrisomy	73	33
C–reactive Protein
<6 mg/dL	77	32	.0026	NS
≥6 mg/dL	23	11
ECOG
<2	48	39	.0040	NS
≥2	52	16
Calcium
<11.5 mg/dL	87	36	<.0001	NS
≥11.5 mg/dL	13	9
Creatinine
<2 mg/dL	78	36	<.0001	NS
≥2 mg/dL	22	9
Albumin
≤3.5 mg/dL	57	39	.0198	NS
>3.5 mg/dL	43	22
Clinical Stage
I & II	38	60	.0010	NS
III	62	19
LDH
<320 U/mL	65	34	.0295	NS
≥320 U/mL	35	16
DNA index
>1	62	39	.0088	NS
≤1	38	15
Hemoglobin
≤9.5 mg/dL	54	60	.0123	NS
>9.5 mg/dL	46	19
Chromosome 9
Trisomy	56	46	.0350	NS
Nontrisomy	44	26
Chromosome 17
Trisomy	22	103	.0260	NS
Nontrisomy	78	33

Variable	Percentage of Cases	Median OS (mo)	P Value Univariate Analysis	P Value Multivariate Analysis
S-phase PC
<3%	68	39	<.0001	.010
≥3%	32	15
β₂microglobulin
<6 mg/L	69	44	.0030	.024
≥6 mg/L	31	15
Chromosome 13
Monosomy	33	14	.0012	.031
Normal	67	60
Chromosome 6
Trisomy	27	70	.0330	.048
Nontrisomy	73	33
C–reactive Protein
<6 mg/dL	77	32	.0026	NS
≥6 mg/dL	23	11
ECOG
<2	48	39	.0040	NS
≥2	52	16
Calcium
<11.5 mg/dL	87	36	<.0001	NS
≥11.5 mg/dL	13	9
Creatinine
<2 mg/dL	78	36	<.0001	NS
≥2 mg/dL	22	9
Albumin
≤3.5 mg/dL	57	39	.0198	NS
>3.5 mg/dL	43	22
Clinical Stage
I & II	38	60	.0010	NS
III	62	19
LDH
<320 U/mL	65	34	.0295	NS
≥320 U/mL	35	16
DNA index
>1	62	39	.0088	NS
≤1	38	15
Hemoglobin
≤9.5 mg/dL	54	60	.0123	NS
>9.5 mg/dL	46	19
Chromosome 9
Trisomy	56	46	.0350	NS
Nontrisomy	44	26
Chromosome 17
Trisomy	22	103	.0260	NS
Nontrisomy	78	33

Abbreviations: ECOG, Eastern Cooperative Oncology Group scale; NS, not significant (P > .05).