Univariate and Multivariate Analysis of Prognostic Factors Influencing Hematopoietic Recovery
| Factors . | P . | |||
|---|---|---|---|---|
| Low Versus Intermediate Group . | High Versus Intermediate Group . | |||
| Univariate . | Multivariate . | Univariate . | Multivariate . | |
| Neutrophil recovery (ANC >1.0 × 109/L) | ||||
| Line of treatment (1st or ≥2nd) | .04 | NS | NS | — |
| No. of previous regimens (≤2 or >3) | NS | — | NS | — |
| Duration of prior chemotherapy (≤ or >5 months) | .003 | NS | NS | — |
| Alkylating agents exposure (≤ or >8 months) | .059 | NS | NS | — |
| Fludarabine administration (yes or no) | .03 | NS | NS | — |
| Disease status at transplant (CR or not) | NS | — | NS | — |
| Bone marrow status at transplant (infiltrated or not) | NS | — | NS | — |
| CD34+ cell dose reinfused | <.0001 | .02 | .003 | — |
| Platelet recovery (platelet counts >50 × 109/L) | ||||
| CD34+ cell dose reinfused3-150 | <.0001 | — | <.0001 | — |
| Factors . | P . | |||
|---|---|---|---|---|
| Low Versus Intermediate Group . | High Versus Intermediate Group . | |||
| Univariate . | Multivariate . | Univariate . | Multivariate . | |
| Neutrophil recovery (ANC >1.0 × 109/L) | ||||
| Line of treatment (1st or ≥2nd) | .04 | NS | NS | — |
| No. of previous regimens (≤2 or >3) | NS | — | NS | — |
| Duration of prior chemotherapy (≤ or >5 months) | .003 | NS | NS | — |
| Alkylating agents exposure (≤ or >8 months) | .059 | NS | NS | — |
| Fludarabine administration (yes or no) | .03 | NS | NS | — |
| Disease status at transplant (CR or not) | NS | — | NS | — |
| Bone marrow status at transplant (infiltrated or not) | NS | — | NS | — |
| CD34+ cell dose reinfused | <.0001 | .02 | .003 | — |
| Platelet recovery (platelet counts >50 × 109/L) | ||||
| CD34+ cell dose reinfused3-150 | <.0001 | — | <.0001 | — |
Abbreviation: NS, not significant.
None of the other above parameters was significant in univariate analysis for platelet recovery.