Sensitivity of Cell Lines to Protein Synthesis Inhibition by DT388–GM-CSF
| Cell Line . | IC50 (×10−13 mol/L) . |
|---|---|
| U937 | 3 |
| HL60BclXL | 10 |
| TF1 | 10 |
| HL60neo | 15 |
| HL60Bcl2 | 20 |
| HL60 | 50 |
| THP-1 | 70 |
| KG1 | 80 |
| KB | 100 |
| HL60/VCR | 120 |
| AML193 | 3,000 |
| K562 | 3,000 |
| CEM | 20,000 |
| HEL92.1.7 | >40,000 |
| LS174T | >40,000 |
| Cell Line . | IC50 (×10−13 mol/L) . |
|---|---|
| U937 | 3 |
| HL60BclXL | 10 |
| TF1 | 10 |
| HL60neo | 15 |
| HL60Bcl2 | 20 |
| HL60 | 50 |
| THP-1 | 70 |
| KG1 | 80 |
| KB | 100 |
| HL60/VCR | 120 |
| AML193 | 3,000 |
| K562 | 3,000 |
| CEM | 20,000 |
| HEL92.1.7 | >40,000 |
| LS174T | >40,000 |
Assays performed in triplicate and mean values displayed as described in text.