Type and Distribution of Posttransplant Liver Disease in Children Undergoing BMT With Normal or Abnormal ALT Values, in Relation to Pre-BMT Viral Markers
| Pre-BMT Findings . | Absent . | Post-BMT Liver Disease . | |||
|---|---|---|---|---|---|
| . | . | MOF . | ALT Elevation: . | . | |
| . | . | . | Transient . | Persistent . | . |
| Pts with normal ALT = 63: | 14 | 2 | 32 | 15 | |
| HBsAg/anti-HCV− = 46: | 11 | 1 | 24 | 10 | |
| HBsAg+ = 0 | — | — | — | — | |
| Anti-HBc + alone = 13 | 3 | 1 | 6 | 3 | |
| HBsAg/anti-HCV+ = 0 | — | — | — | — | |
| Anti-HCV+ = 4 | 0 | 0 | 2 | 2 | |
| Pts with Abnormal ALT = 48: | 11 | 2 | 22 | 13 | |
| HBsAg/anti-HCV− = 40: | 8 | 1 | 19 | 12 | |
| HBsAg+ = 0 | — | — | — | — | |
| Anti-HBc + alone = 8 | 3 | 1 | 3 | 1 | |
| HBsAg/anti-HCV+ = 0 | — | — | — | — | |
| Anti-HCV+ = 0 | — | — | — | — | |
| Pre-BMT Findings . | Absent . | Post-BMT Liver Disease . | |||
|---|---|---|---|---|---|
| . | . | MOF . | ALT Elevation: . | . | |
| . | . | . | Transient . | Persistent . | . |
| Pts with normal ALT = 63: | 14 | 2 | 32 | 15 | |
| HBsAg/anti-HCV− = 46: | 11 | 1 | 24 | 10 | |
| HBsAg+ = 0 | — | — | — | — | |
| Anti-HBc + alone = 13 | 3 | 1 | 6 | 3 | |
| HBsAg/anti-HCV+ = 0 | — | — | — | — | |
| Anti-HCV+ = 4 | 0 | 0 | 2 | 2 | |
| Pts with Abnormal ALT = 48: | 11 | 2 | 22 | 13 | |
| HBsAg/anti-HCV− = 40: | 8 | 1 | 19 | 12 | |
| HBsAg+ = 0 | — | — | — | — | |
| Anti-HBc + alone = 8 | 3 | 1 | 3 | 1 | |
| HBsAg/anti-HCV+ = 0 | — | — | — | — | |
| Anti-HCV+ = 0 | — | — | — | — | |
ALT: transient ≤6 months; persistent >6 months.
Abbreviation: pts, patients.