Table 3. Frequency and Type of Liver... | American Society of Hematology

Table 3.

Frequency and Type of Liver Disease After BMT in 111 Children Undergoing BMT

Type of Liver Disease	No. (%)
MOF	4^3-150 (3.6)
ALT elevation:
Transient (<6 mo)	54^3-151 (49)
Persistent (>6 mo) or recurrent	28 (25)
Symptomatic acute hepatitis	7^3-151 (6)
Cirrhosis	0
Liver failure:
Acute	4^3-150 (3.6)
Chronic	0
Hepatomegaly	4^3-150 (3.6)
Splenomegaly	0
Significant reduction in:
Albumin (<3 g/dL)	4^3-150 (3.6)
PT (<50%)	4^3-150 (3.6)

Type of Liver Disease	No. (%)
MOF	4^3-150 (3.6)
ALT elevation:
Transient (<6 mo)	54^3-151 (49)
Persistent (>6 mo) or recurrent	28 (25)
Symptomatic acute hepatitis	7^3-151 (6)
Cirrhosis	0
Liver failure:
Acute	4^3-150 (3.6)
Chronic	0
Hepatomegaly	4^3-150 (3.6)
Splenomegaly	0
Significant reduction in:
Albumin (<3 g/dL)	4^3-150 (3.6)
PT (<50%)	4^3-150 (3.6)

Abbreviation: PT, prothrombin time.

F3-150

The four children with MOF, which included liver failure, were the same ones with hepatomegaly and significant reduction of serum albumin and prothrombin time.

F3-151

Seven out of 54 children with transient ALT elevation had symptomatic acute hepatitis.

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