Clinical Data on 111 Children Presenting With Normal or Abnormal Transaminases at BMT
| . | ALT Levels Before BMT . | |
|---|---|---|
| . | Normal: . | Abnormal: . |
| . | 63 Cases . | 48 Cases . |
| Mean age at BMT | 9 yr 7 mo | 9 yr 3 mo |
| (range) | (11 mo-18 yr) | (1-17 yr) |
| P value: ns | ||
| Gender: Male/female | 41/22 | 32/16 |
| P value: ns | ||
| No. (%) | No. (%) | |
| Hematologic diagnosis: | ||
| ALL | 37 (59) | 31 (65) |
| AML | 11 (17) | 11 (23) |
| JCML | 2 (3) | 0 |
| CML | 5 (8) | 2 (4) |
| SAA | 4 (6) | 0 |
| RAEB | 3 (5) | 4 (8) |
| Histiocytosis X | 1 (2) | 0 |
| P value: ns | ||
| Disease status | ||
| 1° CR | 11 (17.5) | 11 (23) |
| 2° CR | 31 (49) | 24 (50) |
| >2° CR | 1 (2) | 5 (10) |
| Chronic phase | 5 (8) | 2 (4) |
| Relapse/resistant/blastic transformation | 11 (17.5) | 6 (13) |
| SAA | 4 (6) | 0 (0) |
| P value: ns | ||
| HBsAg+ | 0 | 0 |
| Anti-HBc+ | 13 (21) | 8 (17) |
| Anti-HBc+ and anti-HCV+ | 2 (3) | 0 |
| Anti-HCV+ | 2 (3) | 0 |
| P value: ns | ||
| . | ALT Levels Before BMT . | |
|---|---|---|
| . | Normal: . | Abnormal: . |
| . | 63 Cases . | 48 Cases . |
| Mean age at BMT | 9 yr 7 mo | 9 yr 3 mo |
| (range) | (11 mo-18 yr) | (1-17 yr) |
| P value: ns | ||
| Gender: Male/female | 41/22 | 32/16 |
| P value: ns | ||
| No. (%) | No. (%) | |
| Hematologic diagnosis: | ||
| ALL | 37 (59) | 31 (65) |
| AML | 11 (17) | 11 (23) |
| JCML | 2 (3) | 0 |
| CML | 5 (8) | 2 (4) |
| SAA | 4 (6) | 0 |
| RAEB | 3 (5) | 4 (8) |
| Histiocytosis X | 1 (2) | 0 |
| P value: ns | ||
| Disease status | ||
| 1° CR | 11 (17.5) | 11 (23) |
| 2° CR | 31 (49) | 24 (50) |
| >2° CR | 1 (2) | 5 (10) |
| Chronic phase | 5 (8) | 2 (4) |
| Relapse/resistant/blastic transformation | 11 (17.5) | 6 (13) |
| SAA | 4 (6) | 0 (0) |
| P value: ns | ||
| HBsAg+ | 0 | 0 |
| Anti-HBc+ | 13 (21) | 8 (17) |
| Anti-HBc+ and anti-HCV+ | 2 (3) | 0 |
| Anti-HCV+ | 2 (3) | 0 |
| P value: ns | ||
Abbreviations: ALT, alanine aminotransferase; ns, not significant (P value ≥ .90).