Table 2.

Outgrowth of DT-GM-CSF Exposed, GM-CSF Exposed, and Control AML Cell Populations in SCID Mice

AMLIncubation% Human Cells in SCID Mouse BM*
Control 75 ± 13 
 GM-CSF 64 ± 11 
 DT-GM-CSF 12 ± 8.7 
Control 21 ± 9.2 
 GM-CSF 31 ± 21 
 DT-GM-CSF 
Control 42 ± 9 
 GM-CSF 50 ± 19 
 DT-GM-CSF 21 ± 7 
AMLIncubation% Human Cells in SCID Mouse BM*
Control 75 ± 13 
 GM-CSF 64 ± 11 
 DT-GM-CSF 12 ± 8.7 
Control 21 ± 9.2 
 GM-CSF 31 ± 21 
 DT-GM-CSF 
Control 42 ± 9 
 GM-CSF 50 ± 19 
 DT-GM-CSF 21 ± 7 

Values calculated on the basis of data from five engrafted mice.

*

Mean number of percentage of human cells in SCID mouse BM ± SD.

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