HLA Class II Allele Frequencies in MC Patients Compared With Control Groups
| Alleles . | Patients % n = 25 . | Pathological Controls % n = 30 . | Normal Controls % n = 377 . | RR . | pcI . | pcII . | pcIII . |
|---|---|---|---|---|---|---|---|
| DR1 | 12.0 (3) | 16.7 (5) | 16.7 (63) | 0.7 | NS | NS | NS |
| DR2 | 24.0 (6) | 40.0 (12) | 22.8 (86) | 1.1 | NS | NS | NS |
| DR3 | 40.0 (10) | 23.3 (7) | 15.1 (57) | 3.7 | 0.03 | NS | NS |
| DR4 | 0.0 (0) | 6.7 (2) | 15.9 (60) | 0.1 | NS | NS | NS |
| DR5 | 56.0 (14) | 36.7 (11) | 39.5 (149) | 1.9 | NS | NS | NS |
| DR6 | 24.0 (6) | 30.0 (9) | 26.3 (99) | 0.9 | NS | NS | NS |
| DR7 | 8.0 (2) | 13.3 (4) | 29.7 (112) | 0.2 | NS* | NS | NS |
| DR8 | 4.0 (1) | 0.0 (0) | 7.7 (29) | 0.5 | NS | NS | NS |
| DR9 | 0.0 (0) | 0.0 (0) | 1.1 (4) | 1.6 | NS | NS | NS |
| DR10 | 0.0 (0) | 0.0 (0) | 1.9 (7) | 1.0 | NS | NS | NS |
| DQ1 | 48.0 (12) | 66.7 (20) | 61.8 (233) | 0.6 | NS | NS | NS |
| DQ2 | 40.0 (10) | 33.3 (10) | 43.5 (164) | 0.9 | NS | NS | NS |
| DQ3 | 60.0 (15) | 46.7 (14) | 56.5 (213) | 1.1 | NS | NS | NS |
| B8/DR3 | 48.0 (12) | 23.3 (7) | 19.1 (72) | 3.9 | 0.04 | NS | NS |
| B8, DR3 | 32.0 (8) | 6.7 (2) | 6.1 (23) | 7.2 | 0.0003 | NS | NS* |
| Alleles . | Patients % n = 25 . | Pathological Controls % n = 30 . | Normal Controls % n = 377 . | RR . | pcI . | pcII . | pcIII . |
|---|---|---|---|---|---|---|---|
| DR1 | 12.0 (3) | 16.7 (5) | 16.7 (63) | 0.7 | NS | NS | NS |
| DR2 | 24.0 (6) | 40.0 (12) | 22.8 (86) | 1.1 | NS | NS | NS |
| DR3 | 40.0 (10) | 23.3 (7) | 15.1 (57) | 3.7 | 0.03 | NS | NS |
| DR4 | 0.0 (0) | 6.7 (2) | 15.9 (60) | 0.1 | NS | NS | NS |
| DR5 | 56.0 (14) | 36.7 (11) | 39.5 (149) | 1.9 | NS | NS | NS |
| DR6 | 24.0 (6) | 30.0 (9) | 26.3 (99) | 0.9 | NS | NS | NS |
| DR7 | 8.0 (2) | 13.3 (4) | 29.7 (112) | 0.2 | NS* | NS | NS |
| DR8 | 4.0 (1) | 0.0 (0) | 7.7 (29) | 0.5 | NS | NS | NS |
| DR9 | 0.0 (0) | 0.0 (0) | 1.1 (4) | 1.6 | NS | NS | NS |
| DR10 | 0.0 (0) | 0.0 (0) | 1.9 (7) | 1.0 | NS | NS | NS |
| DQ1 | 48.0 (12) | 66.7 (20) | 61.8 (233) | 0.6 | NS | NS | NS |
| DQ2 | 40.0 (10) | 33.3 (10) | 43.5 (164) | 0.9 | NS | NS | NS |
| DQ3 | 60.0 (15) | 46.7 (14) | 56.5 (213) | 1.1 | NS | NS | NS |
| B8/DR3 | 48.0 (12) | 23.3 (7) | 19.1 (72) | 3.9 | 0.04 | NS | NS |
| B8, DR3 | 32.0 (8) | 6.7 (2) | 6.1 (23) | 7.2 | 0.0003 | NS | NS* |
*P = .03.