Thymidine Incorporation of Flavopiridol-Treated Human Lymphocytes After Mitogen Stimulation in Vitro
| Pretreatment . | Stimulation Indices From 3H-Methyl Thymidine Incorporation According to the Mitogen Used . | |||
|---|---|---|---|---|
| CON-A 1.56 μg/mL . | PHA-P 1.56 μg/mL . | PWM 1.56 μg/mL . | Anti-CD3 10 ng/mL . | |
| Flavopiridol (nmol/L) | ||||
| 0 | 252.2 | 155.8 | 86.4 | 35.3 |
| 100 | 68.1 | 89.9 | 23.2 | −0.7 |
| 250 | 1.0 | 4.7 | 2.8 | −0.9 |
| 500 | −0.3 | −0.4 | 0.1 | −0.8 |
| Actinomycin D (μg/mL) | ||||
| 10 | −0.5 | −0.1 | −0.1 | −0.9 |
| Pretreatment . | Stimulation Indices From 3H-Methyl Thymidine Incorporation According to the Mitogen Used . | |||
|---|---|---|---|---|
| CON-A 1.56 μg/mL . | PHA-P 1.56 μg/mL . | PWM 1.56 μg/mL . | Anti-CD3 10 ng/mL . | |
| Flavopiridol (nmol/L) | ||||
| 0 | 252.2 | 155.8 | 86.4 | 35.3 |
| 100 | 68.1 | 89.9 | 23.2 | −0.7 |
| 250 | 1.0 | 4.7 | 2.8 | −0.9 |
| 500 | −0.3 | −0.4 | 0.1 | −0.8 |
| Actinomycin D (μg/mL) | ||||
| 10 | −0.5 | −0.1 | −0.1 | −0.9 |