Table 3.

Factors Independently Related to Overall Survival in 1,710 Cases of Diffuse Large-Cell Lymphoma

FactorRelative RiskP
Age (≤60 v >60) 1.72 <.0001 
Ann Arbor stage (I-II v III-IV) 1.60 <.0001 
LDH level (≤1 × normal v >1 × normal) 1.59 <.0001 
Performance status (0-1 v 2-4) 1.59 <.0001 
Histology (anaplastic v nonanaplastic) 1.60 .0028 
B symptoms (no v yes) 1.07 .0097 
Serum albumin level (≤30 g/L v <30 g/L) 1.21 .01 
Bone marrow involvement (no v yes) 1.04 .036 
Extranodal involvement (≤1 site v >1 site) 1.18 .05 
FactorRelative RiskP
Age (≤60 v >60) 1.72 <.0001 
Ann Arbor stage (I-II v III-IV) 1.60 <.0001 
LDH level (≤1 × normal v >1 × normal) 1.59 <.0001 
Performance status (0-1 v 2-4) 1.59 <.0001 
Histology (anaplastic v nonanaplastic) 1.60 .0028 
B symptoms (no v yes) 1.07 .0097 
Serum albumin level (≤30 g/L v <30 g/L) 1.21 .01 
Bone marrow involvement (no v yes) 1.04 .036 
Extranodal involvement (≤1 site v >1 site) 1.18 .05 
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