Expression of Bomapin in Normal and Malignant Hematopoiesis
| Tissue . | Number of Samples . | Bomapin Expression Level . | ||
|---|---|---|---|---|
| High . | Medium . | Low or Undetectable . | ||
| Bone marrow | ||||
| Normal | 6 | 0 | 6 | 0 |
| Acute myeloid leukemia | 7 | 1 | 4 | 2 |
| Peripheral blood | ||||
| Normal | 6 | 0 | 0 | 6 |
| Chronic lymphocytic leukemia | 6 | 0 | 0 | 6 |
| Chronic myeloid leukemia | 6 | 0 | 2 | 4 |
| Chronic myelomonocytic leukemia | 6 | 0 | 5 | 1 |
| Acute myeloid leukemia | 6 | 1 | 3 | 2 |
| Acute lymphocytic leukemia | 5 | 0 | 1 | 4 |
| Tissue . | Number of Samples . | Bomapin Expression Level . | ||
|---|---|---|---|---|
| High . | Medium . | Low or Undetectable . | ||
| Bone marrow | ||||
| Normal | 6 | 0 | 6 | 0 |
| Acute myeloid leukemia | 7 | 1 | 4 | 2 |
| Peripheral blood | ||||
| Normal | 6 | 0 | 0 | 6 |
| Chronic lymphocytic leukemia | 6 | 0 | 0 | 6 |
| Chronic myeloid leukemia | 6 | 0 | 2 | 4 |
| Chronic myelomonocytic leukemia | 6 | 0 | 5 | 1 |
| Acute myeloid leukemia | 6 | 1 | 3 | 2 |
| Acute lymphocytic leukemia | 5 | 0 | 1 | 4 |
Bomapin expression was analyzed by PCR as described in Materials and Methods. The expression levels were classified as either low or undetectable, medium, or high (Fig 1). PCR amplifications for β-actin were performed independently and only samples with comparable β-actin PCR products were used for analysis.