Table 2.

Summary of the Six Surviving Children Born With Homozygous α-Thalassemia

Previous Birth of Hydropic Infant Birth Transfusion Treatment Duration in Hospital After Birth Follow-UpReferences
No  Caesarean section at 32 wk  Postdelivery transfusion  48 d At 6 yr, delay in speech and hearing 62, 64 
Yes  Caesarean section at 28 wk  Postdelivery transfusion  73 d  At 5 yr, normal development 63, 64 
Not  recorded  Vaginal delivery with breech presentation at 28 wk  Postdelivery transfusion  64 d  At 10 mo, mild gross motor delay  64 
No Caesarean section at 31 wk, as part of triplet delivery Postdelivery transfusion  2½ mo  At 2 yr, spastic quadriplegia and profound developmental delay  65 
Yes Caesarean section at 34 wk  Intrauterine transfusion beginning at 25 wk  11 d  Several congenital anomalies. At 2 yr, developmental delay in cognitive and motor functions  55, 66 
No Caesarean section at 37 wk  Intrauterine transfusion beginning at 32 wk  30 d  At 3 yr, normal neurological assessment 67 
Previous Birth of Hydropic Infant Birth Transfusion Treatment Duration in Hospital After Birth Follow-UpReferences
No  Caesarean section at 32 wk  Postdelivery transfusion  48 d At 6 yr, delay in speech and hearing 62, 64 
Yes  Caesarean section at 28 wk  Postdelivery transfusion  73 d  At 5 yr, normal development 63, 64 
Not  recorded  Vaginal delivery with breech presentation at 28 wk  Postdelivery transfusion  64 d  At 10 mo, mild gross motor delay  64 
No Caesarean section at 31 wk, as part of triplet delivery Postdelivery transfusion  2½ mo  At 2 yr, spastic quadriplegia and profound developmental delay  65 
Yes Caesarean section at 34 wk  Intrauterine transfusion beginning at 25 wk  11 d  Several congenital anomalies. At 2 yr, developmental delay in cognitive and motor functions  55, 66 
No Caesarean section at 37 wk  Intrauterine transfusion beginning at 32 wk  30 d  At 3 yr, normal neurological assessment 67 

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