Features of Patients With CNS Recurrence
| Neurologic symptoms at recurrence | |
| Coma | 1 |
| Seizures | 1 |
| Mental status changes, lethargy, confusion | 10 |
| Headache | 7 |
| Cranial nerve palsy | 7 |
| Peripheral sensory or motor symptoms | 5 |
| Gait and balance | 2 |
| Lumbar puncture | |
| Not done | 2 |
| Negative | 1 |
| Lymphoma cells | 19 |
| Other abnormalities/no lymphoma cells | 2 |
| Radiologic findings | |
| Leptomeningeal involvement | 7 |
| Brain parenchymal involvement | 8 |
| Negative radiologic studies | 7 |
| No radiologic studies | 3 |
| Status of systemic disease | |
| Simultaneous CNS and systemic relapse | 5 |
| Systemic relapse with 40-180 days after CNS relapse | 7 |
| Death within 40 days after CNS recurrence without systemic restaging | 7 |
| Survival beyond 40 days after CNS recurrence, no systemic recurrence | 5 |
| Neurologic symptoms at recurrence | |
| Coma | 1 |
| Seizures | 1 |
| Mental status changes, lethargy, confusion | 10 |
| Headache | 7 |
| Cranial nerve palsy | 7 |
| Peripheral sensory or motor symptoms | 5 |
| Gait and balance | 2 |
| Lumbar puncture | |
| Not done | 2 |
| Negative | 1 |
| Lymphoma cells | 19 |
| Other abnormalities/no lymphoma cells | 2 |
| Radiologic findings | |
| Leptomeningeal involvement | 7 |
| Brain parenchymal involvement | 8 |
| Negative radiologic studies | 7 |
| No radiologic studies | 3 |
| Status of systemic disease | |
| Simultaneous CNS and systemic relapse | 5 |
| Systemic relapse with 40-180 days after CNS relapse | 7 |
| Death within 40 days after CNS recurrence without systemic restaging | 7 |
| Survival beyond 40 days after CNS recurrence, no systemic recurrence | 5 |