Table 1. Gelatinase Levels After Injury... | American Society of Hematology

Table 1.

Gelatinase Levels After Injury of Femoral or Carotid Artery of MMP-3^+/+ or MMP-3^−/− Mice as Determined With Arterial Extracts on Gelatin Zymography

	Carotid Artery				Femoral Artery
	MMP-3^+/+		MMP-3^−/−		MMP-3^+/+		MMP-3^−/−
	Control	1 Week	Control	1 Week	Control	1 Week	Control	1 Week
70 kD proMMP-2	30 ± 4	59 ± 4^-151	21 ± 3	80 ± 7^-151	24 ± 4	50 ± 10^-150	24 ± 2	74 ± 12^-151
61 kD MMP-2	ND	30 ± 6	ND	38 ± 4	ND	24 ± 3	ND	25 ± 4
65 kD proMMP-2	200 ± 26	330 ± 44^-150	180 ± 14	420 ± 48^-151	180 ± 22	320 ± 25^-151	190 ± 21	410 ± 27^-151
58 kD MMP-2	5.6 ± 1.6	160 ± 23^-151	5.4 ± 2.1	240 ± 13^-151	8.5 ± 1.2 (3)	150 ± 31^-150	5.8 ± 0.82 (3)	170 ± 13^-151
94 kD proMMP-9	8.0 ± 3.3 (1)	83 ± 13^-151	1.7 ± 0.96 (1)	74 ± 12^-151	1.5 ± 0.17 (3)	120 ± 52^-151	3.0 ± 0.80	120 ± 42^-150
83 kD MMP-9	ND	10 ± 0.8	ND	16 ± 5	ND	19 ± 10	ND	18 ± 9

	Carotid Artery				Femoral Artery
	MMP-3^+/+		MMP-3^−/−		MMP-3^+/+		MMP-3^−/−
	Control	1 Week	Control	1 Week	Control	1 Week	Control	1 Week
70 kD proMMP-2	30 ± 4	59 ± 4^-151	21 ± 3	80 ± 7^-151	24 ± 4	50 ± 10^-150	24 ± 2	74 ± 12^-151
61 kD MMP-2	ND	30 ± 6	ND	38 ± 4	ND	24 ± 3	ND	25 ± 4
65 kD proMMP-2	200 ± 26	330 ± 44^-150	180 ± 14	420 ± 48^-151	180 ± 22	320 ± 25^-151	190 ± 21	410 ± 27^-151
58 kD MMP-2	5.6 ± 1.6	160 ± 23^-151	5.4 ± 2.1	240 ± 13^-151	8.5 ± 1.2 (3)	150 ± 31^-150	5.8 ± 0.82 (3)	170 ± 13^-151
94 kD proMMP-9	8.0 ± 3.3 (1)	83 ± 13^-151	1.7 ± 0.96 (1)	74 ± 12^-151	1.5 ± 0.17 (3)	120 ± 52^-151	3.0 ± 0.80	120 ± 42^-150
83 kD MMP-9	ND	10 ± 0.8	ND	16 ± 5	ND	19 ± 10	ND	18 ± 9

Data represent lysis, expressed per mg protein. Numbers in brackets indicate the numbers of arteries with ND levels. Data are mean ± SEM of five experiments.

Abbreviation: ND, not detectable.

F0-150

P < .05 versus control.

F0-151

P < .01 versus control.

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