Table 2.

Effect of Growth Factor Activation on Surface Adhesion Molecule Expression in CD34+Cells

Mobilized PBPCCytokine-Activated Mobilized PBPC
LFA-1 56 (6-84) 56 (51-89) 
L-selectin 57 (23-87) 35 (22-76) 
VLA-4 99 (85-99) 98 (94-99) 
ICAM-1 31 (2.3-81) 50 (33-77) 
PECAM-1 98 (95-99) 97 (95-99) 
Mobilized PBPCCytokine-Activated Mobilized PBPC
LFA-1 56 (6-84) 56 (51-89) 
L-selectin 57 (23-87) 35 (22-76) 
VLA-4 99 (85-99) 98 (94-99) 
ICAM-1 31 (2.3-81) 50 (33-77) 
PECAM-1 98 (95-99) 97 (95-99) 

Freshly isolated mobilized PBPCs were compared with cytokine-activated (3 days stimulation with IL-3 12 ng/mL, SCF 10 ng/mL, and IL-6 10 ng/mL) mobilized PBPCs for expression of each surface molecule. Data are median percentage and range (in brackets) of cells staining positive for the antigen.