Table 3.

Correlation of Overall Survival With Clinical and Biologic Features of 103 Patients With AML

Clinical Factor (no.) Log-Rank (P) g-Wilcoxon (P)
Age (yr)  
 ≤50 (50)  
 >50 (53)  .005 <.001  
Sex  
 M (63)  
 F (40)  NS NS  
 WBC (×109/L)  
 ≤50 (74) 
 >50 (28)  .004  <.001  
LDH  
 ≥N, ≤5 × N (87)  
 >5 × N (14)  .003  <.001  
CD7 
 Negative (67)  
 Positive (17)  NS  NS 
Chromosomal aberration  
 − (40)  
 + (61)  NS NS  
 − (40)  
 t(8;21) (13)  .041 NS  
 t(15;17) (14)  <.005  <.005 
 inv(16) (3)  NS  NS  
 11q23 (3) NS  NS  
 MAKA (5)  NS NS  
 Others (24)  NS  NS 
nm23-H1 Index  
 ≤100 (71)  
 >100 (32) <.001  <.005  
nm23-H2 Index  
 ≤110 (77) 
 >110 (26)  NS  <.05 
Clinical Factor (no.) Log-Rank (P) g-Wilcoxon (P)
Age (yr)  
 ≤50 (50)  
 >50 (53)  .005 <.001  
Sex  
 M (63)  
 F (40)  NS NS  
 WBC (×109/L)  
 ≤50 (74) 
 >50 (28)  .004  <.001  
LDH  
 ≥N, ≤5 × N (87)  
 >5 × N (14)  .003  <.001  
CD7 
 Negative (67)  
 Positive (17)  NS  NS 
Chromosomal aberration  
 − (40)  
 + (61)  NS NS  
 − (40)  
 t(8;21) (13)  .041 NS  
 t(15;17) (14)  <.005  <.005 
 inv(16) (3)  NS  NS  
 11q23 (3) NS  NS  
 MAKA (5)  NS NS  
 Others (24)  NS  NS 
nm23-H1 Index  
 ≤100 (71)  
 >100 (32) <.001  <.005  
nm23-H2 Index  
 ≤110 (77) 
 >110 (26)  NS  <.05 

Abbreviation: NS, not significant.

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