Table 2.

Effect of Single Versus Daily Dose Administration of PEG-rmMGDF on Day 5 MPV

Group MPV (fL)
Experiment 1Experiment 2
Control  4.26 ± 0.12  5.02 ± 0.08 
 (4)  (4)  
MGDF 100 μg/kg × 1 5.00 ± 0.10  5.31 ± 0.04 
 (5)  (6)  
MGDF 100 μg/kg daily × 5  7.52 ± 0.15*  7.81 ± 0.09† 
 (5)  (6) 
Group MPV (fL)
Experiment 1Experiment 2
Control  4.26 ± 0.12  5.02 ± 0.08 
 (4)  (4)  
MGDF 100 μg/kg × 1 5.00 ± 0.10  5.31 ± 0.04 
 (5)  (6)  
MGDF 100 μg/kg daily × 5  7.52 ± 0.15*  7.81 ± 0.09† 
 (5)  (6) 

Values shown represent mean ± SEM. Numbers in parentheses indicate number of mice per group.

*

Significantly different from MPV of mice treated with MGDF 100 μg/kg × 1, P = .008, Wilcoxon-Mann-Whitney.

Significantly different from MPV of mice treated with MGDF 100 μg/kg × 1, P = .002, Wilcoxon-Mann-Whitney.

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