Expression of Differentiation, Activation, and NK Markers on CD4, CD8, and CD8dull Subsets
| Subset* . | Cells/μL† . | Frequency of Subset With Phenotype‡ . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | . | CD45RA+ . | CD45RA− . | CD45RA− . | CD45RA+ . | CD57+ . | CD8αα+ . | CD16+ . | CD56+ . | TcRγδ+ . |
| . | . | CD62L+ . | CD62L− . | CD62L+ . | CD62L− . | . | . | . | . | . |
| CD4+CD8− | 630 | 5.9 | 57 | 34 | 2.9 | 18 | NA | 0.6 | 6.5 | 0.5 |
| (240-1100) | (0.1-14) | (42-86) | (14-47) | (0.4-7.4) | (11-33) | (0.1-1.1) | (1.7-18) | (0.1-1.1) | ||
| CD8+CD4− | 620 | 7.5 | 48 | 14 | 30 | 52 | 5.7 | 3.3 | 24 | 1.5 |
| (270-830) | (1.5-17) | (22-77) | (11-17) | (11-57) | (38-78) | (0.8-16) | (1.7-6.1) | (11-36) | (0.7-2.5) | |
| CD8dullCD4+ | 55 | 1.5 | 60 | 7.2 | 27 | 79 | 93 | 2.2 | 41 | 1.3 |
| (27-68) | (0.2-2.4) | (16-92) | (5.3-10) | (0.6-76) | (59-92) | (83-99) | (0.6-3.1) | (14-74) | (0.8-2.0) | |
| CD8dullCD4− | 103 | 4.3 | 40 | 5.8 | 49 | 65 | 59 | 8.2 | 36 | 27 |
| (90-114) | (2.1-6.5) | (13-66) | (5.6-5.9) | (23-75) | (49-77) | (50-71) | (3.7-17) | (18-56) | (5.0-52) | |
| Subset* . | Cells/μL† . | Frequency of Subset With Phenotype‡ . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| . | . | CD45RA+ . | CD45RA− . | CD45RA− . | CD45RA+ . | CD57+ . | CD8αα+ . | CD16+ . | CD56+ . | TcRγδ+ . |
| . | . | CD62L+ . | CD62L− . | CD62L+ . | CD62L− . | . | . | . | . | . |
| CD4+CD8− | 630 | 5.9 | 57 | 34 | 2.9 | 18 | NA | 0.6 | 6.5 | 0.5 |
| (240-1100) | (0.1-14) | (42-86) | (14-47) | (0.4-7.4) | (11-33) | (0.1-1.1) | (1.7-18) | (0.1-1.1) | ||
| CD8+CD4− | 620 | 7.5 | 48 | 14 | 30 | 52 | 5.7 | 3.3 | 24 | 1.5 |
| (270-830) | (1.5-17) | (22-77) | (11-17) | (11-57) | (38-78) | (0.8-16) | (1.7-6.1) | (11-36) | (0.7-2.5) | |
| CD8dullCD4+ | 55 | 1.5 | 60 | 7.2 | 27 | 79 | 93 | 2.2 | 41 | 1.3 |
| (27-68) | (0.2-2.4) | (16-92) | (5.3-10) | (0.6-76) | (59-92) | (83-99) | (0.6-3.1) | (14-74) | (0.8-2.0) | |
| CD8dullCD4− | 103 | 4.3 | 40 | 5.8 | 49 | 65 | 59 | 8.2 | 36 | 27 |
| (90-114) | (2.1-6.5) | (13-66) | (5.6-5.9) | (23-75) | (49-77) | (50-71) | (3.7-17) | (18-56) | (5.0-52) | |
Abbreviation: NA, not applicable.
Subsets are defined on the expression of CD3, CD4, and CD8, as shown in Fig 1 and 7.
Absolute count of each subset, expressed as cells per microliter of whole blood. The average and range are given for 3 to 5 individuals.
Frequency of each subset expressing the marker or combination of markers shown (as shown by the example in Fig 7). The average and range are given for 2 to 5 individuals.