Physical Performance, Hematologic Values, and Secondary Effects of Chemotherapy in the Two Groups
| . | Training . | Controls . | Significance of P . | 95% CI . |
|---|---|---|---|---|
| Hospital admission: | ||||
| Maximal performance (km/h)* | 7.91 ± 1.2 | 7.51 ± 1.3 | 0.18 | −0.18; 1.17 |
| Maximal heart rate in the stress-test (bpm) | 170 ± 18 | 168 ± 16 | 0.58 | −6; 10 |
| Percentage of estimated maximal heart rate (220 − age) | 94 ± 7% | 94 ± 8% | 0.89 | −3; 4 |
| Hemoglobin concentration (g/dL) | 10.5 ± 1.6 | 10.7 ± 1.3 | 0.50 | −0.98; 0.48 |
| Hematocrit | 30 ± 4% | 31 ± 4% | 0.42 | −2.96; 1.26 |
| Discharge from hospital: | ||||
| Maximal performance (km/h)* | 6.85 ± 1.1 | 6.08 ± 1.3 | 0.04 (1) | 0.12; 1.41 |
| Maximal heart rate in the stress-test (bpm) | 166 ± 21 | 168 ± 19 | 0.84 | −11; 9 |
| Percentage of estimated maximal heart rate (220 − age) | 92 ± 10% | 93 ± 9% | 0.69 | −6; 4 |
| Hemoglobin concentration (g/dL) | 9.7 ± 0.9 | 9.5 ± 1.1 | 0.49 | −0.31; 0.65 |
| Hematocrit | 27 ± 2% | 27 ± 3% | 0.71 | −1.27; 1.72 |
| Loss of physical performance during hospitalization (%) | 14 ± 9% | 19 ± 11% | 0.05 | −10.43; 0.20 |
| Duration of neutropenia <0.5 × 109/L (d) | 6.6 ± 1.5 | 7.6 ± 1.6 | 0.01 | −1.71; −0.16 |
| Duration of thrombopenia <50 × 109/L (d) | 10.9 ± 3 | 12.4 ± 3.7 | 0.06 | −3.14; 0.14 |
| Blood transfusions (U) | 3.3 ± 1.4 | 3.3 ± 2 | 0.92 | −0.89; 0.82 |
| Platelets transfusions (U) | 19.5 ± 14.1 | 26.9 ± 19.5 | 0.06 | −15.7; 0.8 |
| In-hospital days | 13.6 ± 2.2 | 15.2 ± 3.6 | 0.03 | −3.07; −0.10 |
| Severity of mucositis† | 2.34 ± 0.8 | 2.43 ± 0.55 | 0.38 | −0.42; 0.24 |
| Severity of diarrhea† | 1.90 ± 1 | 2.37 ± 0.86 | 0.04 | −0.92; −0.01 |
| Severity of infection† | 2 ± 0.5 | 2.1 ± 0.39 | 0.33 | −0.23; 0.47 |
| Severity of pain† | 1.87 ± 0.75 | 2.4 ± 0.49 | 0.01 | −0.68; −0.56 |
| . | Training . | Controls . | Significance of P . | 95% CI . |
|---|---|---|---|---|
| Hospital admission: | ||||
| Maximal performance (km/h)* | 7.91 ± 1.2 | 7.51 ± 1.3 | 0.18 | −0.18; 1.17 |
| Maximal heart rate in the stress-test (bpm) | 170 ± 18 | 168 ± 16 | 0.58 | −6; 10 |
| Percentage of estimated maximal heart rate (220 − age) | 94 ± 7% | 94 ± 8% | 0.89 | −3; 4 |
| Hemoglobin concentration (g/dL) | 10.5 ± 1.6 | 10.7 ± 1.3 | 0.50 | −0.98; 0.48 |
| Hematocrit | 30 ± 4% | 31 ± 4% | 0.42 | −2.96; 1.26 |
| Discharge from hospital: | ||||
| Maximal performance (km/h)* | 6.85 ± 1.1 | 6.08 ± 1.3 | 0.04 (1) | 0.12; 1.41 |
| Maximal heart rate in the stress-test (bpm) | 166 ± 21 | 168 ± 19 | 0.84 | −11; 9 |
| Percentage of estimated maximal heart rate (220 − age) | 92 ± 10% | 93 ± 9% | 0.69 | −6; 4 |
| Hemoglobin concentration (g/dL) | 9.7 ± 0.9 | 9.5 ± 1.1 | 0.49 | −0.31; 0.65 |
| Hematocrit | 27 ± 2% | 27 ± 3% | 0.71 | −1.27; 1.72 |
| Loss of physical performance during hospitalization (%) | 14 ± 9% | 19 ± 11% | 0.05 | −10.43; 0.20 |
| Duration of neutropenia <0.5 × 109/L (d) | 6.6 ± 1.5 | 7.6 ± 1.6 | 0.01 | −1.71; −0.16 |
| Duration of thrombopenia <50 × 109/L (d) | 10.9 ± 3 | 12.4 ± 3.7 | 0.06 | −3.14; 0.14 |
| Blood transfusions (U) | 3.3 ± 1.4 | 3.3 ± 2 | 0.92 | −0.89; 0.82 |
| Platelets transfusions (U) | 19.5 ± 14.1 | 26.9 ± 19.5 | 0.06 | −15.7; 0.8 |
| In-hospital days | 13.6 ± 2.2 | 15.2 ± 3.6 | 0.03 | −3.07; −0.10 |
| Severity of mucositis† | 2.34 ± 0.8 | 2.43 ± 0.55 | 0.38 | −0.42; 0.24 |
| Severity of diarrhea† | 1.90 ± 1 | 2.37 ± 0.86 | 0.04 | −0.92; −0.01 |
| Severity of infection† | 2 ± 0.5 | 2.1 ± 0.39 | 0.33 | −0.23; 0.47 |
| Severity of pain† | 1.87 ± 0.75 | 2.4 ± 0.49 | 0.01 | −0.68; −0.56 |