Table 1.

Interaction of Promoter and Hypoxia-Inducible Enhancer

Combination in Plasmids (promoter/enhancer)Hypoxic Induction
P19 Hep3B
Epo/Epo No  Yes  
LDHA/LDHA  Yes  Yes  
Epo/LDHA  Yes* Yes  
LDHA/Epo  No  Yes 
Combination in Plasmids (promoter/enhancer)Hypoxic Induction
P19 Hep3B
Epo/Epo No  Yes  
LDHA/LDHA  Yes  Yes  
Epo/LDHA  Yes* Yes  
LDHA/Epo  No  Yes 

*Less inducible than in Hep3B (see Fig 8A and B).

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