Table 1.

Catalase Inhibits Dose-Dependently Platelet Aggregation Induced by Collagen But Not by ADP or Thrombin

Control Catalase (250 U/mL) Catalase (1,000 U/mL)
Collagen (2 μg/mL)  63.2 ± 9.4  31.0 ± 11.2* 6.1 ± 1.4†  
ADP (2 μmol/L)  52.7 ± 3.3 50.7 ± 4.7  44.0 ± 3.4  
Thrombin (0.1 U/mL) 92.0 ± 3.1  91.0 ± 2.6  84.2 ± 2.5 
Control Catalase (250 U/mL) Catalase (1,000 U/mL)
Collagen (2 μg/mL)  63.2 ± 9.4  31.0 ± 11.2* 6.1 ± 1.4†  
ADP (2 μmol/L)  52.7 ± 3.3 50.7 ± 4.7  44.0 ± 3.4  
Thrombin (0.1 U/mL) 92.0 ± 3.1  91.0 ± 2.6  84.2 ± 2.5 

The percentage of maximal aggregation 5 minutes after stimulation is shown. Data are expressed as the mean ± SEM of five separate experiments.

F0-150

P < .05.

F0-151

P < .01.

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