Coefficients of Determination (R2) for Relationships Between Levels of Bcl-2 Family Members and Other Prognostic Factors
| . | AML . | |||
|---|---|---|---|---|
| Bcl-2 . | Bcl-xL . | Mcl-1 . | Bax . | |
| Bcl-xL | .001 | — | — | — |
| Mcl-1 | .19-150 | .04 | — | — |
| Bax | .18-150 | .04 | .15-150 | — |
| WBC | .006 | .08 | .0001 | .02 |
| Age | .003 | .03 | .001 | .12-151 |
| ALL | ||||
| Bcl-2 | Bcl-xL | Mcl-1 | Bax | |
| Bcl-xL | .09-152 | — | — | — |
| Mcl-1 | .62-150 | .17-152 | — | — |
| Bax | .004 | .25-153 | .02 | — |
| WBC | .02 | .07 | .03 | .007 |
| Age | .02 | .002 | .02 | .02 |
| . | AML . | |||
|---|---|---|---|---|
| Bcl-2 . | Bcl-xL . | Mcl-1 . | Bax . | |
| Bcl-xL | .001 | — | — | — |
| Mcl-1 | .19-150 | .04 | — | — |
| Bax | .18-150 | .04 | .15-150 | — |
| WBC | .006 | .08 | .0001 | .02 |
| Age | .003 | .03 | .001 | .12-151 |
| ALL | ||||
| Bcl-2 | Bcl-xL | Mcl-1 | Bax | |
| Bcl-xL | .09-152 | — | — | — |
| Mcl-1 | .62-150 | .17-152 | — | — |
| Bax | .004 | .25-153 | .02 | — |
| WBC | .02 | .07 | .03 | .007 |
| Age | .02 | .002 | .02 | .02 |
Correlation coefficients were calculated for the indicated pairs of continuous variables using data obtained from the 54 pretreatment AML samples or 23 pretreatment ALL samples that contained >80% blasts. WBC, peripheral leukocyte count at diagnosis.
P < .01.
P = .02.
Weak inverse correlations that do not reach statistical significance due to small sample size.
P = .04.