FACS Immunophenotype of KSHV and Control Cell Lines
| Cell Lines . | Daudi . | HBL-6 . | BCP-1 . |
|---|---|---|---|
| B-cell markers | |||
| CD10 | + | − | − |
| CD19 | + | − | − |
| CD20 | + | − | − |
| CD22 | + | − | − |
| CD79a | + | + | − |
| CD79b | ND | − | − |
| CD39 | ND | − | − |
| CD72 | ND | − | − |
| Activation markers | |||
| CD23 | + | + | + |
| CD25 | + | + | + |
| CD30 | + | − | − |
| CD38 | + | + | +* |
| Cytoadhesins | |||
| CD11a | + | − | − |
| CD11b | − | + | + |
| CD11c | ND | − | − |
| CD18 | + | − | − |
| CD29 | + | + | + |
| 8A2 | + | + | + |
| CD31 | + | − | − |
| CD44 | + | − | − |
| CD49d | + | + | − |
| CD49e | − | + | − |
| CD54 | + | − | − |
| CD58 | − | + | − |
| CD62L | + | − | − |
| CD62E | + | − | − |
| EMA | − | + | + |
| Miscellaneous markers | |||
| Tdt | ND | − | − |
| CD34 | − | − | − |
| CD43 | + | + | + |
| CD45 | + | − | − |
| HLA-DR | + | − | − |
| Cell Lines . | Daudi . | HBL-6 . | BCP-1 . |
|---|---|---|---|
| B-cell markers | |||
| CD10 | + | − | − |
| CD19 | + | − | − |
| CD20 | + | − | − |
| CD22 | + | − | − |
| CD79a | + | + | − |
| CD79b | ND | − | − |
| CD39 | ND | − | − |
| CD72 | ND | − | − |
| Activation markers | |||
| CD23 | + | + | + |
| CD25 | + | + | + |
| CD30 | + | − | − |
| CD38 | + | + | +* |
| Cytoadhesins | |||
| CD11a | + | − | − |
| CD11b | − | + | + |
| CD11c | ND | − | − |
| CD18 | + | − | − |
| CD29 | + | + | + |
| 8A2 | + | + | + |
| CD31 | + | − | − |
| CD44 | + | − | − |
| CD49d | + | + | − |
| CD49e | − | + | − |
| CD54 | + | − | − |
| CD58 | − | + | − |
| CD62L | + | − | − |
| CD62E | + | − | − |
| EMA | − | + | + |
| Miscellaneous markers | |||
| Tdt | ND | − | − |
| CD34 | − | − | − |
| CD43 | + | + | + |
| CD45 | + | − | − |
| HLA-DR | + | − | − |
Cells from all three lines were negative for T-cell (CD3, CD5 and CD7) and myelymonocytic (CD13 and CD14) markers.
Abbreviation: ND, not determined.
The activation marker CD38 was absent on native BCP-1 cells, but repeatedly became upregulated after growth in the peritoneal cavity of mice.