Table 2. Surface Expression of Platelet... | American Society of Hematology

Table 2.

Surface Expression of Platelet Receptors

Receptor/ Subunit	¹²⁵I-Antibody (concentration)	Molecules of Antibody/Platelet		Surface Expression (% of normal)
Receptor/ Subunit	¹²⁵I-Antibody (concentration)	Patient	Control	Surface Expression (% of normal)
GPIbα	6D1 (20 μg/mL)	19,100 18,900	17,100 18,200	108.0
GPIIb/IIIa	10E5 (20 μg/mL)	700 1,400	38,500 40,900	2.6
GPIIb/IIIa + α_vβ₃	c7E3 Fab (18 μg/mL)	2,800 2,800	49,200 54,900	5.4
GPIIIa	7H2 (20 μg/mL)	6,200	53,000	12.0
α_vβ₃	LM609 (38 ng/mL) (162 ng/mL)	25 53	15 25	172.0 212.0

Receptor/ Subunit	¹²⁵I-Antibody (concentration)	Molecules of Antibody/Platelet		Surface Expression (% of normal)
Receptor/ Subunit	¹²⁵I-Antibody (concentration)	Patient	Control	Surface Expression (% of normal)
GPIbα	6D1 (20 μg/mL)	19,100 18,900	17,100 18,200	108.0
GPIIb/IIIa	10E5 (20 μg/mL)	700 1,400	38,500 40,900	2.6
GPIIb/IIIa + α_vβ₃	c7E3 Fab (18 μg/mL)	2,800 2,800	49,200 54,900	5.4
GPIIIa	7H2 (20 μg/mL)	6,200	53,000	12.0
α_vβ₃	LM609 (38 ng/mL) (162 ng/mL)	25 53	15 25	172.0 212.0