Table 1. Hematologic Features of the... | American Society of Hematology

Table 1.

Hematologic Features of the T39P, T117, and T127 T-ALLs

	Age (yr)/Sex	WBC (10⁹/L)	TS	TAL1 d	Phenotype	Clinical Outcome	MTS1α Expression		Rb Expression
	Age (yr)/Sex	WBC (10⁹/L)	TS	TAL1 d	Phenotype	Clinical Outcome	RNA	Protein (p16^INK4a)	Rb	Rb-P
T39	8/M	140	N	+	CD7−,2−,1−,4−,8−,3−	CR; relapse 10 mo later and death.	+++	+++	+	+++
T117	22/M	189	N	−	CD7+,2+,1+,4+,8+,3−	CR; allogenic intrafamilial HLA matched bone marrow transplantation in 1st CR. Death by aspergillosis.	++	++	+	++
T127	16/F	440	N	+	CD7+,2+,1+/−,4+/−,8+,3+	CR; relapse 9 mo later after autologous bone marrow transplantation and death.	+	+	+	+

	Age (yr)/Sex	WBC (10⁹/L)	TS	TAL1 d	Phenotype	Clinical Outcome	MTS1α Expression		Rb Expression
	Age (yr)/Sex	WBC (10⁹/L)	TS	TAL1 d	Phenotype	Clinical Outcome	RNA	Protein (p16^INK4a)	Rb	Rb-P
T39	8/M	140	N	+	CD7−,2−,1−,4−,8−,3−	CR; relapse 10 mo later and death.	+++	+++	+	+++
T117	22/M	189	N	−	CD7+,2+,1+,4+,8+,3−	CR; allogenic intrafamilial HLA matched bone marrow transplantation in 1st CR. Death by aspergillosis.	++	++	+	++
T127	16/F	440	N	+	CD7+,2+,1+/−,4+/−,8+,3+	CR; relapse 9 mo later after autologous bone marrow transplantation and death.	+	+	+	+

Abbreviations: WBC, white blood cell count; TS; tumoral syndrome; TAL1 d, TAL1 deletion (ie, SIL-TAL1 rearrangement); CR, complete remission; Rb-P, phosphorylated Rb.