Causes of Death Among Patients With CMV gB Types 1-4
| Cause of Death* . | gB1 (%) . | gB2 (%) . | gB3 (%) . | gB4 (%) . | Mix (%) . |
|---|---|---|---|---|---|
| CMV (n = 46) | 21 (15.4) | 11 (23.9) | 11 (15.9) | 2 (8.7) | 1 (14.3) |
| Relapse (n = 73) | 45 (33.1) | 10 (21.7) | 14 (20.3) | 3 (13.0) | 1 (14.3) |
| Other (n = 31) | 15 (11.0) | 7 (15.2) | 4 (5.8) | 4 (17.4) | 1 (14.3) |
| Unknown (n = 8) | 4 (2.9) | 2 (4.3) | 1 (1.4) | 1 (4.3) | 0 (0) |
| Myelosuppression (n = 24) | 4 (2.9) | 0 (0) | 15 (21.7) | 4 (17.4) | 1 (14.3) |
| Total dead | 89 | 30 | 45 | 14 | 4 |
| Total patients | 136 | 46 | 69 | 23 | 7 |
| Cause of Death* . | gB1 (%) . | gB2 (%) . | gB3 (%) . | gB4 (%) . | Mix (%) . |
|---|---|---|---|---|---|
| CMV (n = 46) | 21 (15.4) | 11 (23.9) | 11 (15.9) | 2 (8.7) | 1 (14.3) |
| Relapse (n = 73) | 45 (33.1) | 10 (21.7) | 14 (20.3) | 3 (13.0) | 1 (14.3) |
| Other (n = 31) | 15 (11.0) | 7 (15.2) | 4 (5.8) | 4 (17.4) | 1 (14.3) |
| Unknown (n = 8) | 4 (2.9) | 2 (4.3) | 1 (1.4) | 1 (4.3) | 0 (0) |
| Myelosuppression (n = 24) | 4 (2.9) | 0 (0) | 15 (21.7) | 4 (17.4) | 1 (14.3) |
| Total dead | 89 | 30 | 45 | 14 | 4 |
| Total patients | 136 | 46 | 69 | 23 | 7 |
Data represent the absolute number of patients and the percentages of patients dead of a specific cause among all patients with that gB type.
The causes of death were determined from archived research files. CMV deaths include deaths due to CMV pneumonia, disseminated CMV, as well as gastrointestinal CMV. Relapse was documented by histology and cytogenetics. Other causes included GVHD, veno-occlusive disease, and multiorgan failure. Deaths attributed to myelosuppression were caused by infectious complications of neutropenia (ANC < 500), none were associated with host-mediated graft rejection. Eight patients had incomplete files and were lost to follow-up.