Table 1. Normalization of Deficient 125... | American Society of Hematology

Table 1.

Normalization of Deficient ¹²⁵I-NGF Binding of mi/mi CMCs by Introduction of cDNA Encoding +-MITF

Cell Type	¹²⁵I-NGF Binding (cpm/10⁶ cells)^*
	Total	Nonspecific	Specific

+/+ CMCs	3,192 ± 139	1,535 ± 237	1,657 ± 140
mi/mi CMCs	2,035 ± 78^†	1,673 ± 185	362 ± 78^†
mi/mi CMCs overexpressing +-MITF	3,030 ± 124^‡	1,958 ± 205	1,432 ± 124^‡
mi/mi CMCs overexpressing mi-MITF	2,067 ± 124^†	1,665 ± 234	402 ± 124^†

Cell Type	¹²⁵I-NGF Binding (cpm/10⁶ cells)^*
	Total	Nonspecific	Specific

+/+ CMCs	3,192 ± 139	1,535 ± 237	1,657 ± 140
mi/mi CMCs	2,035 ± 78^†	1,673 ± 185	362 ± 78^†
mi/mi CMCs overexpressing +-MITF	3,030 ± 124^‡	1,958 ± 205	1,432 ± 124^‡
mi/mi CMCs overexpressing mi-MITF	2,067 ± 124^†	1,665 ± 234	402 ± 124^†

CMCs were incubated for 45 minutes with ¹²⁵I-NGF in α-MEM containing 10% FCS.

Mean ± SE of 3 experiments.

P < .01 by t-test v +/+ CMCs.

P < .01 by t-test v nontreated mi/mi CMCs.