Effect of Recombinant Apolipoprotein(a) on Monocyte Migration Across Polycarbonate Membranes
| . | No. of Migrated Cells . |
|---|---|
| Control | 7.1 ± 0.3 |
| FMLP (10 nmol/L) | 22.9 ± 1.53-150 |
| Apo(a) (μg/mL) | |
| 150 | 22.1 ± 1.03-150 |
| 100 | 16.7 ± 1.13-150 |
| 50 | 14.7 ± 0.43-150 |
| 25 | 11.8 ± 0.73-150 |
| . | No. of Migrated Cells . |
|---|---|
| Control | 7.1 ± 0.3 |
| FMLP (10 nmol/L) | 22.9 ± 1.53-150 |
| Apo(a) (μg/mL) | |
| 150 | 22.1 ± 1.03-150 |
| 100 | 16.7 ± 1.13-150 |
| 50 | 14.7 ± 0.43-150 |
| 25 | 11.8 ± 0.73-150 |
Monocytes were allowed to migrate for 90 minutes across polycarbonate membranes with a pore size of 5 μm. Different dilutions of recombinant apo(a) were added to the lower compartments of the Transwell chambers. Results represent the mean ± SEM for migrated cells in 7 oil-immersion fields counted in triplicate from 4 experiments.
P < .01 versus HBSS-BSA 0.4% controls by Neuman-Keuls test.