Effect of Crotalin, PGI2, Halysin and Ancrod on the Lapsed Time in Inducing Thrombus Formation Caused by Irradiation of Mesenteric Venules of Fluorescein Sodium-Treated Mice
| Administration . | Occlusion Time (s) . |
|---|---|
| Saline | 105 ± 12 (6) |
| PGI2, 2 μg/kg/min | 148 ± 16 (6)3-150,3-151 |
| Halysin, 10 mg/kg | 155 ± 20 (6)3-150,3-151 |
| Ancrod, 1 U/kg | 176 ± 31 (6)3-150,3-151 |
| Crotalin, 300 μg/kg | 293 ± 38 (6)3-150 |
| Administration . | Occlusion Time (s) . |
|---|---|
| Saline | 105 ± 12 (6) |
| PGI2, 2 μg/kg/min | 148 ± 16 (6)3-150,3-151 |
| Halysin, 10 mg/kg | 155 ± 20 (6)3-150,3-151 |
| Ancrod, 1 U/kg | 176 ± 31 (6)3-150,3-151 |
| Crotalin, 300 μg/kg | 293 ± 38 (6)3-150 |
Platelet-rich thrombus formation was induced as described in Table2. The occlusion time was measured 10 to 20 minutes after the administration of halysin, ancrod, crotalin, and PGI2. Values are presented as mean ± SEM (n = 6).
P < .05 as compared with the control group (receiving normal saline).
P < .05 as compared with crotalin group.