Hematologic Values From fit1 Mutants and Wild-Type Littermates
| Group . | n . | Retic . | WBC . | RBC . | HGB . | HCT . | MCV . | MCH . | MCHC . |
|---|---|---|---|---|---|---|---|---|---|
| . | . | (%) . | (×106/mL) . | (×109/mL) . | (g/dL) . | (%) . | (FL) . | (pg) . | (g/dL) . |
| Control | 24 | 4.4 ± 1.1* | 6.5 ± 1.3 | 9.2 ± 0.9 | 13.9 ± 1.4 | 44.7 ± 3.7 | 47.5 ± 3.1 | 15.2 ± 0.8 | 32.0 ± 1.8 |
| 494SB | 1 | — | 6.2 | 4.1 | 4.4 | 19.8 ± 4.9† | 32.0 | 10.7 | 33.3 |
| 764SB | 14 | — | 3.8 ± 1.8 | 6.3 ± 1.2 | 7.3 ± 1.5 | 24.7 ± 5.4 | 33.2 ± 2.5 | 11.1 ± 0.7 | 33.5 ± 1.9 |
| 3452SB | 5 | — | 6.6 ± 1.4 | 9.4 ± 1.6 | 13.1 ± 1.8 | 34.5 ± 5.4 | 44.0 ± 3.7 | 14.1 ± 1.1 | 32.1 ± 0.4 |
| 4226SB | 11 | — | 5.7 ± 1.5 | 7.3 ± 1.0 | 8.1 ± 1.3 | 26.7 ± 3.6 | 35.3 ± 1.5 | 11.2 ± 0.6 | 31.5 ± 0.9 |
| 4397SB | 10 | 15.8 ± 4.2* | 3.5 ± 1.5 | 5.6 ± 1.3 | 5.6 ± 1.0 | 16.7 ± 5.3 | 28.2 ± 2.5 | 10.3 ± 0.7 | 36.9 ± 3.8 |
| Group . | n . | Retic . | WBC . | RBC . | HGB . | HCT . | MCV . | MCH . | MCHC . |
|---|---|---|---|---|---|---|---|---|---|
| . | . | (%) . | (×106/mL) . | (×109/mL) . | (g/dL) . | (%) . | (FL) . | (pg) . | (g/dL) . |
| Control | 24 | 4.4 ± 1.1* | 6.5 ± 1.3 | 9.2 ± 0.9 | 13.9 ± 1.4 | 44.7 ± 3.7 | 47.5 ± 3.1 | 15.2 ± 0.8 | 32.0 ± 1.8 |
| 494SB | 1 | — | 6.2 | 4.1 | 4.4 | 19.8 ± 4.9† | 32.0 | 10.7 | 33.3 |
| 764SB | 14 | — | 3.8 ± 1.8 | 6.3 ± 1.2 | 7.3 ± 1.5 | 24.7 ± 5.4 | 33.2 ± 2.5 | 11.1 ± 0.7 | 33.5 ± 1.9 |
| 3452SB | 5 | — | 6.6 ± 1.4 | 9.4 ± 1.6 | 13.1 ± 1.8 | 34.5 ± 5.4 | 44.0 ± 3.7 | 14.1 ± 1.1 | 32.1 ± 0.4 |
| 4226SB | 11 | — | 5.7 ± 1.5 | 7.3 ± 1.0 | 8.1 ± 1.3 | 26.7 ± 3.6 | 35.3 ± 1.5 | 11.2 ± 0.6 | 31.5 ± 0.9 |
| 4397SB | 10 | 15.8 ± 4.2* | 3.5 ± 1.5 | 5.6 ± 1.3 | 5.6 ± 1.0 | 16.7 ± 5.3 | 28.2 ± 2.5 | 10.3 ± 0.7 | 36.9 ± 3.8 |
Control mice [cch +/cch+, cch+/c26DVT, and cch+/c fit1m (where m designates the individual fit1 alleles)] and mutants (c fit1m/c26DVT, shown in the table by the allele designations) were analyzed at 3 to 5 weeks of age. Data are mean ± standard deviation.
Abbreviations: Retic, reticulocytes; WBC, white blood cells; RBC, red blood cells; HGB, hemoglobin; HCT, hematocrit; MCV, mean cell volume; MCH, mean cell hemoglobin; MCHC, mean cell hemoglobin concentration.
n = 3.
n = 8.