Comparison of IPSS and M.D. Anderson Patients
. | IPSS . | M.D. Anderson . | P Value . |
---|---|---|---|
Patients | 816 | 219 | |
Median age* | 69 | 65 | |
RA/RAS (%) | 51 | 45 | .08 |
RAEB (%) | 26 | 28 | .41 |
RAEB-t (%) | 7 | 24 | <.001 |
CMML (%) | 15 | 3 | <.001 |
Median platelet count/neutrophil count/hemoglobin† | >100/>1.5 | 72/0.9/9.6 | |
2-3 Cytopenias (%) | 42 | 66 | <.001 |
Cyto good (%) | 70 | 55 | <.001 |
Cyto inter (%) | 14 | 17 | .23 |
Cyto poor (%) | 16 | 28 | <.001 |
IPSS score | |||
Low (%) | 33 | 13 | <.001 |
INT-1 (%) | 38 | 41 | .56 |
INT-2 (%) | 22 | 30 | .008 |
High (%) | 7 | 16 | <.001 |
. | IPSS . | M.D. Anderson . | P Value . |
---|---|---|---|
Patients | 816 | 219 | |
Median age* | 69 | 65 | |
RA/RAS (%) | 51 | 45 | .08 |
RAEB (%) | 26 | 28 | .41 |
RAEB-t (%) | 7 | 24 | <.001 |
CMML (%) | 15 | 3 | <.001 |
Median platelet count/neutrophil count/hemoglobin† | >100/>1.5 | 72/0.9/9.6 | |
2-3 Cytopenias (%) | 42 | 66 | <.001 |
Cyto good (%) | 70 | 55 | <.001 |
Cyto inter (%) | 14 | 17 | .23 |
Cyto poor (%) | 16 | 28 | <.001 |
IPSS score | |||
Low (%) | 33 | 13 | <.001 |
INT-1 (%) | 38 | 41 | .56 |
INT-2 (%) | 22 | 30 | .008 |
High (%) | 7 | 16 | <.001 |
% of patients age >60 years 75% v 65% in the IPSS and MDA groups, respectively (P = .005).
% of patients with platelet count < 100 37% v 63% in the IPSS and MDA groups, respectively (P < .001). % of patients with neutrophil count <1.5 46% v 65% in the IPSS and MDA groups, respectively (P <.001). % of patients with Hg <10 54% v 60% in the IPSS and MDA groups, respectively (P = .11).