Table 1.

Protocol for Prophylactic Platelet Transfusion in AML (FAB M 3 Excluded): No Sign of Major Bleeding or Retinal Bleeding With Impairment of Vision

Group A Group B
Morning platelet count of <10 × 109 platelets/L  Morning platelet count of <20 × 109 platelets/L 
 <15 × 109 platelets/L in case of: 
  Fever >38.5°C and rapid decrease in platelet count 
  Plasma coagulation factor deficiencies due to sepsis or leukemia  
  Hyperleukocytosis >50 × 109/L  
Group A Group B
Morning platelet count of <10 × 109 platelets/L  Morning platelet count of <20 × 109 platelets/L 
 <15 × 109 platelets/L in case of: 
  Fever >38.5°C and rapid decrease in platelet count 
  Plasma coagulation factor deficiencies due to sepsis or leukemia  
  Hyperleukocytosis >50 × 109/L  

Major bleeding is defined in the text.

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